Evidence map›Paper›PMID 27325942›Full record

ArticleHeart Asia2010

Effect of smoking on age at the time of coronary artery bypass graft surgery; baseline data results from the ROSETTA-CABG registry.

Rashid Chaudhry, Fahd A Chaudhry, Thao Huynh, Ellis Lader, Saira Rashid, Karen Okrainec, Karen Wou, Mark J Eisenberg, ROSETTA-CABG Investigators

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In one paragraph

Article in Heart Asia, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rashid ChaudhryDepartment of Cardiology, Lahore 54590, Pakistan.
Fahd A ChaudhryUniversity Physician Health Care, University of Arizona, Tucson, Arizona, USA.
Thao HuynhDivision of Cardiology, Montreal General Hospital, Montreal, Quebec, Canada.
Ellis LaderMid Valley Cardiology, Kingston, New York, USA.
Saira RashidKing Edward Medical University, Lahore, Pakistan.
Karen OkrainecDivision of Internal Medicine, McGill University Health Center, Montreal, Quebec, Canada.
Karen WouDivision of Internal Medicine, McGill University Health Center, Montreal, Quebec, Canada.
Mark J EisenbergDivisions of Cardiology and Clinical Epidemiology, Jewish General Hospital, Montreal, Quebec, Canada; Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada.
ROSETTA-CABG Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary artery disease (CAD) is a leading cause of death. The aetiology of this disease is not known, but many important risk factors have been recognised.

objectiveTo evaluate the effect of smoking on age at the time of coronary artery bypass graft surgery (CABG), and to examine this finding in the light of medical literature.

methodsThe authors recruited patients immediately after CABG in a prospective, study in 16 centres and enrolled 408 patients, of which 395 were ultimately analysed.

resultsAmong the 395 patients analysed, there were 60 smokers and 335 non-smokers. The smokers were 8.4 years younger than non-smokers at the time of index CABG. The average age of smokers was 55.79.0 years, and that of non-smokers was 64.1±9.9 years (p<0.001). Hyperlipidaemia was present in 76.7% of smokers and 74.6% of non-smokers (p-NS). Hypertension was present in 58.3% of smokers and 63.9% of non-smokers (p-NS). Diabetes mellitus was present in 21.3% of smokers and 29.3% of non smokers (p-NS). Left ventricular ejection fraction was 53.0±10.5% in smokers and 53.3 ±13.8% in non-smokers (p-NS). Myocardial infarction had occurred in 41.7% of smokers and 35.5% of non-smokers (p-NS).

conclusionSmoking accelerates atherosclerosis and coronary thrombosis resulting in severe form of CAD that cannot be managed by medications or PCI, and requires coronary artery bypass graft surgery (CABG) 8.4 years earlier than non-smokers.

Indexed as

acute myocardial infarctionatherosclerosiscoronary artery bypass graftcoronary artery diseaserisk factorsSmokers

Identifiers

PMID27325942
PMCPMC4898517

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.