Evidence map›Paper›PMID 27325804›Full record

ArticleThe American journal of tropical medicine and hygiene2016

Rickettsia sp. Strain Atlantic Rainforest Infection in a Patient from a Spotted Fever-Endemic Area in Southern Brazil.

Felipe S Krawczak, Sebastián Muñoz-Leal, Ana Carolina Guztzazky, Stefan V Oliveira, Fabiana C P Santos, Rodrigo N Angerami, Jonas Moraes-Filho, Julio C de Souza, Marcelo B Labruna

Abstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Ticks on wild vertebrates necropsied in a veterinary pathology service in central Brazil: species richness and pathogen screening.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2026
    Article
  2. Article
  3. Eco-epidemiological analysis of Rickettsia parkeri in domestic dogs and Amblyomma ovale ticks in the Atlantic rainforest of Northeast Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2024
    Article
  4. Article
  5. Article
  6. Detection ofAnimals : an open access journal from MDPI · 2023
    Article
  7. Diversity of rickettsiae in ticks (Acari: Ixodidae) collected from wild vertebrates in part of the Amazon, Cerrado, and Pantanal biomes in Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2023
    Article
  8. Article
  9. A new focus of spotted fever caused by Rickettsia parkeri in Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Fatal case of spotted fever in a patient from Northeastern Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Felipe S KrawczakFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Sebastián Muñoz-LealFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Ana Carolina GuztzazkyFundação Universidade Regional de Blumenau, Blumenau, Santa Catarina, Brazil.
Stefan V OliveiraSecretaria de Vigilância em Saúde, Ministério da Saúde, Brasília, Distrito Federal, Brazil.
Fabiana C P SantosInstituto Adolfo Lutz, Secretaria de Estado da Saúde, São Paulo, Brazil.
Rodrigo N AngeramiHospital das Clínicas, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil.
Jonas Moraes-FilhoFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Julio C de SouzaFundação Universidade Regional de Blumenau, Blumenau, Santa Catarina, Brazil.
Marcelo B LabrunaFaculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil. labruna@usp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Santa Catarina State in southern Brazil is the state with the second highest number of laboratory-confirmed cases of spotted fever illness in Brazil. However, all these cases were confirmed solely by serological analysis (seroconversion to spotted fever group rickettsiae), which has not allowed identification of the rickettsial agent. Here, a clinical case of spotted fever illness from Santa Catarina is shown by seroconversion and molecular analysis to be caused by Rickettsia sp. strain Atlantic rainforest. This is the third confirmed clinical case due to this emerging rickettsial agent in Brazil. Like the previous two cases, the patient presented an inoculation eschar at the tick bite site. Our molecular diagnosis was performed on DNA extracted from the crust removed from the eschar. These results are supported by previous epidemiological studies in Santa Catarina, which showed that nearly 10% of the most common human-biting ticks were infected by Rickettsia sp. strain Atlantic rainforest.

Indexed as

Rickettsia rickettsiiAnimalsBrazilFemaleHumansRocky Mountain Spotted FeverTicksYoung Adult

Identifiers

PMID27325804
PMCPMC5014257

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.