Observational studyThe American journal of tropical medicine and hygiene2016
Burden of Liver Abscess and Survival Risk Score in Thailand: A Population-Based Study.
Observational study in The American journal of tropical medicine and hygiene, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 26 citations in OpenAlex.
- Etiology, Risk Factors, and Antimicrobial Resistance in Recurrent Pyogenic Liver Abscesses: A Six-Year Analysis.Infection and drug resistance · 2025Article
- Clinical characteristics and management of liver abscess in The Gambia, a resource-limited country.BMC gastroenterology · 2024Article
- Guidelines for Antibiotics Prescription in Critically Ill Patients.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Liver abscess in the caudate lobe caused by Klebsiella pneumoniae: a rare case report and literature review.BMC infectious diseases · 2024Review
- Risk factors indicating the need for surgical therapy in patients with pyogenic liver abscesses.Langenbeck's archives of surgery · 2023Article
- Thrombocytopenia as an important determinant of poor prognosis in patients with pyogenic liver abscess: a retrospective case series.Frontiers in surgery · 2023Article
- Changes in clinical and CT manifestations related to liver abscesses in patients with vs. without basic diabetes mellitus before and after CT-guided interventional therapy: An observational study.Clinics (Sao Paulo, Brazil) · 2023Observational
- Sarcopenia as an important determinant for adverse outcomes in patients with pyogenic liver abscess.PeerJ · 2023Article
- Clinical characteristics and management of 1572 patients with pyogenic liver abscess: A 12-year retrospective study.Liver international : official journal of the International Association for the Study of the Liver · 2021Article
- Amoebic Liver Abscesses in Fiji: Epidemiology, Clinical Presentation and Comparison of Percutaneous Aspiration and Percutaneous Catheter Drainage.World journal of surgery · 2020Article
- Effect of diabetes mellitus on short-term prognosis of 227 pyogenic liver abscess patients after hospitalization.BMC infectious diseases · 2020Article
- Guidelines for Antibiotic Prescription in Intensive Care Unit.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Amoebic Liver Abscess and Indigenous Alcoholic Beverages in the Tropics.Journal of tropical medicine · 2018Review
- A significant cancer burden and high mortality of intrahepatic cholangiocarcinoma in Thailand: a nationwide database study.BMC gastroenterology · 2017Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In Thailand, the burden of liver abscess, a life-threatening infectious disease, has not been thoroughly evaluated. We developed a predictive scoring system to estimate survival of patients with liver abscess using information from the 2008-2013 Nationwide Hospital Admission Data to evaluate the burden of liver abscess in Thailand. All patients with primary diagnosis of pyogenic liver abscess (PLA) and amoebic liver abscess (ALA) were included. Epidemiological data, baseline characteristics, hospital course, and survival were analyzed. Overall, 11,296 admissions comprising 8,423 patients from 844 hospitals across Thailand were eligible for analysis. The mean age was 52 ± 17 years and 66.1% of patients were male. ALA was significantly prevalent in southern and western border regions of Thailand, and PLA occurred nationwide. The highest incidence of liver abscess occurred in the rainy season (June-November, P < 0.01). The median length of hospital stay was 8 days (interquartile range = 4-13 days), and mean direct cost of hospitalization was 846 ± 1,574 USD. The overall inhospital mortality rate was 2.8%. Incidence of ALA decreased over the 5-year study period, whereas PLA incidence increased (P < 0.01). Using multivariable Cox regression methods with stepwise variable selection, we developed a final model with five highly significant baseline parameters associated with increased 60-day mortality: older age, PLA, underlying chronic kidney disease, cirrhosis, and human immunodeficiency virus infection. Range of estimated probability of 60-day survival was 95-16% at cumulative risk score 0-13. This simplified score is practical, and may help clinicians prioritize patients requiring more intensive care.
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