ArticleScientific reports2016
Multifunctional Fe3O4 @ Au core/shell nanostars: a unique platform for multimode imaging and photothermal therapy of tumors.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
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- Core-Shell Plasmonic Nanocomposites with Synergistic Photothermal and Photochemical Activity for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Nanomaterials in PCR: exploring light-to-heat conversion mechanisms and microfluidic integration.Microsystems & nanoengineering · 2025Review
- Comparative Study of Catalytic Activity of Recyclable Au/FeChemistryOpen · 2024Article
- Ultrasound-mediated delivery of Pik3cb shRNA using magnetic nanoparticles for the treatment of in-stent restenosis in a rat balloon-injured model.Journal of radiation research · 2024Article
- 3D modeling of in vivo MRI-guided nano-photothermal therapy mediated by magneto-plasmonic nanohybrids.Biomedical engineering online · 2023Article
- Light-Induced Clusterization of Gold Nanoparticles: A New Photo-Triggered Antibacterial againstNanomaterials (Basel, Switzerland) · 2023Article
- Gold-iron oxide (Au/FeFrontiers in molecular biosciences · 2023Article
- Polyethyleneimine-Based Drug Delivery Systems for Cancer Theranostics.Journal of functional biomaterials · 2022Review
- Engineering Gold Shelled Nanomagnets for Pre-Setting the Operating Temperature for Magnetic Hyperthermia.Nanomaterials (Basel, Switzerland) · 2022Article
- Safe and efficient 2D molybdenum disulfide platform for cooperative imaging-guided photothermal-selective chemotherapy: A preclinical study.Journal of advanced research · 2022Article
- Monitoring of the choline/lipid ratio byLasers in medical science · 2022Article
- Advances and Potentials of Polydopamine Nanosystem in Photothermal-Based Antibacterial Infection Therapies.Frontiers in pharmacology · 2022Review
- A 2D nanotheranostic platform based on graphene oxide and phase-change materials for bimodal CT/MR imaging, NIR-activated drug release, and synergistic thermo-chemotherapy.Nanotheranostics · 2022Article
- Dendrimer-modified gold nanorods as a platform for combinational gene therapy and photothermal therapy of tumors.Journal of experimental & clinical cancer research : CR · 2021Article
- The Multifunctionally Graded System for a Controlled Size Effect on Iron Oxide-Gold Based Core-Shell Nanoparticles.Nanomaterials (Basel, Switzerland) · 2021Article
- Synthesis and Stabilization of Support-Free Mesoporous Gold Nanoparticles.Nanomaterials (Basel, Switzerland) · 2020Article
- Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics.Theranostics · 2020Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We herein report the development of multifunctional folic acid (FA)-targeted Fe3O4 @ Au nanostars (NSs) for targeted multi-mode magnetic resonance (MR)/computed tomography (CT)/photoacoustic (PA) imaging and photothermal therapy (PTT) of tumors. In this present work, citric acid-stabilized Fe3O4/Ag composite nanoparticles prepared by a mild reduction route were utilized as seeds and exposed to the Au growth solution to induce the formation of Fe3O4 @ Au core/shell NSs. Followed by successive decoration of thiolated polyethyleneimine (PEI-SH), FA via a polyethylene glycol spacer, and acetylation of the residual PEI amines, multifunctional Fe3O4 @ Au NSs were formed. The designed multifunctional NSs possess excellent colloidal stability, good cytocompatibility in a given concentration range, and specific recognition to cancer cells overexpressing FA receptors. Due to co-existence of Fe3O4 core and star-shaped Au shell, the NSs can be used for MR and CT imaging of tumors, respectively. Likewise, the near infrared plasmonic absorption feature also enables the NSs to be used for PA imaging and PTT of tumors. Our study clearly demonstrates a unique theranostic nanoplatform that can be used for high performance multi-mode imaging-guided PTT of tumors, which may be extendable for theranostics of different diseases in translational medicine.
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