Evidence map›Paper›PMID 27324843›Full record

ArticleJournal of the American Society of Hypertension : JASH2016

Is there an association between the prevalence of atrial fibrillation and severity and control of hypertension? The REasons for Geographic And Racial Differences in Stroke study.

Hemal Bhatt, Christopher M Gamboa, Monika M Safford, Elsayad Z Soliman, Stephen P Glasser

Abstract read
In one paragraph

Article in Journal of the American Society of Hypertension : JASH, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. New-onset hypertension as a contributing factor to the incidence of atrial fibrillation in the elderly.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  3. Article
  4. Article
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hemal BhattDivision of Cardiovascular Disease, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA. Electronic address: cardiothorax@gmail.com.
Christopher M GamboaDivision of Preventive Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.
Monika M SaffordDivision of Preventive Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA; Division of General Internal Medicine, Weill Cornell Medical College, New York, NY, USA.
Elsayad Z SolimanDivision of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Stephen P GlasserDivision of Preventive Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA.

Funding

VCID and Stroke in a Bi-racial National CohortU01NS041588 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI CUSHMAN, MARY, HOWARD, GEORGE · 2002 to 2022
$96.0M
REGARDS - MI StudyR01HL080477 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI LEVITAN, EMILY B, SAFFORD, MONIKA M · 2006 to 2020
$11.6M
MECHANISMS OF HYPERTENSION AND CARDIOVASCULAR DISEASEST32HL007457 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Martin E Young · 1985 to 2026
$8.6M
Building Capacity for Cardiometabolic Outcomes ResearchK24HL111154 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SAFFORD, MONIKA M · 2012 to 2015
$556k
NHLBI NIH HHS K24 HL111154NHLBI NIH HHS R01 HL080477NHLBI NIH HHS T32 HL007457NINDS NIH HHS U01 NS041588
6 · The paper itself

Abstract

The association of atrial fibrillation (AF) with the severity and control of hypertension (HTN) remains unclear. We analyzed data from the national biracial cohort of REasons for Geographic And Racial Differences in Stroke study. The AF prevalence ratios were estimated and full multivariable adjustment included demographics, risk factors, medication adherence, HTN duration, and antihypertensive medication classes. Of the 30,018 study participants (8.6% with AF), 4386 had normotension (4.3% with AF), 5916 had prehypertension (4.3 with AF%), 12,294 had controlled HTN (11.2% with AF), 5587 had uncontrolled HTN (8.1% with AF), 547 had controlled apparent treatment-resistant hypertension (aTRH) (19.2% with AF), and 1288 had uncontrolled aTRH (15.5% with AF). Compared with normotension, the AF prevalence ratios for prehypertension, controlled HTN, uncontrolled HTN, controlled aTRH, and uncontrolled aTRH groups in fully adjusted model were 1.01 (95% confidence interval: 0.84, 1.21), 1.42 (1.18, 1.71), 1.37 (1.14, 1.65), 1.17 (0.86, 1.58), and 1.42 (1.10, 1.84), respectively (P < .001). The prevalence of AF was similar among persons with HTN regardless of blood pressure level and antihypertensive treatment resistance.

Indexed as

AgedAge FactorsAntihypertensive AgentsAtrial FibrillationBlack PeopleBlood Pressure DeterminationCohort StudiesCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedPrehypertensionPrevalenceRisk FactorsAntihypertensive AgentsAntihypertensive medicationsbeta-blockersblood pressuretreatment-resistant hypertension

Identifiers

PMID27324843
PMCPMC4958539

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.