ReviewSchmerz (Berlin, Germany)2016
[Stress-induced hyperalgesia (SIH) as a consequence of emotional deprivation and psychosocial traumatization in childhood : Implications for the treatment of chronic pain].
Review in Schmerz (Berlin, Germany), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- [General treatment principles, coordination of care and patient education in fibromyalgia syndrome : Updated guidelines 2017 and overview of systematic review articles].Schmerz (Berlin, Germany) · 2017Pooled it
- [Critical Life Events in the Developement of Chronic Musculoskeletal Pain : Results of a qualitative study].Schmerz (Berlin, Germany) · 2026Article
- [Chronic lateral epicondylopathy : What do we know about tennis elbow?]Orthopadie (Heidelberg, Germany) · 2025Review
- [Myofascial pain syndrome-a neurovegetative complaints pattern].Orthopadie (Heidelberg, Germany) · 2024Article
- [Treatment expectations of multimodal pain therapy inpatients].Schmerz (Berlin, Germany) · 2024Article
- Overview: Chronic Pain and Cannabis-Based Medicines.Pharmacopsychiatry · 2024Review
- Microbial Dysbiosis and Male Infertility: Understanding the Impact and Exploring Therapeutic Interventions.Journal of personalized medicine · 2023Review
- Subjective perception of life stress events affects long-term pain: the role of resilience.BMC psychology · 2022Article
- Neurohumoral Profiles and Childhood Adversity of Patients with Multisomatoform Disorder and Pain as the Leading Bodily Symptom.Disease markers · 2022Article
- Stress and Pain. Predictive (Neuro)Pattern Identification for Chronic Back Pain: A Longitudinal Observational Study.Frontiers in medicine · 2022Article
- Guilt is effectively induced by a written auto-biographical essay but not reduced by experimental pain.Frontiers in behavioral neuroscience · 2022Article
- Transient receptor potential ankyrin 1 ion channel expressed by the Edinger-Westphal nucleus contributes to stress adaptation in murine model of posttraumatic stress disorder.Frontiers in cell and developmental biology · 2022Article
- When a Head Is about to Burst: Attachment Mediates the Relationship Between Childhood Trauma and Migraine.International journal of environmental research and public health · 2020Article
- Childhood traumatization is associated with differences in TRPA1 promoter methylation in female patients with multisomatoform disorder with pain as the leading bodily symptom.Clinical epigenetics · 2019Article
- Rethinking the criteria for fibromyalgia in 2019: the ABC indicators.Journal of pain research · 2019Article
- Somatosensory profiles of patients with chronic myogenic temporomandibular disorders in relation to their painDETECT score.BMC oral health · 2018Article
- Effects of Post-Weaning Chronic Stress on Nociception, Spinal Cord μ-Opioid, and α2-Adrenergic Receptors Expression in Rats and Their Offspring.Journal of molecular neuroscience : MN · 2018Article
- Facts and myths pertaining to fibromyalgia.Dialogues in clinical neuroscience · 2018Review
- [Stress-induced hyperalgesia].Schmerz (Berlin, Germany) · 2017Article
- [Psychosocial stressors and pain sensitivity in chronic pain disorder with somatic and psychological factors (F45.41)].Schmerz (Berlin, Germany) · 2017Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is now widely recognized that in many chronic pain syndromes the intensity and severity of individually perceived pain does not correlate consistently with the degree of peripheral nervous system tissue damage or with the intensity of primary afferent or spinal nociceptive neurone activity. In particular, stress and anxiety exert modulatory influences on pain depending on the nature, duration and intensity of the stressor and developmental influences on the maturation of the stress as well as the pain system. In some chronic pain syndromes, e. g. fibromyalgia, TMD or somatoform disorders, no nociceptive or neuropathic input is detectable. We summarise the studies investigating the neural substrates and neurobiological mechanisms of stress-induced hyperalgesia (SIH) in animals and humans. The review provides new perspectives and challenges for the current and future treatment of chronic pain.
Indexed as
Identifiers
27324753What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.