Evidence map›Paper›PMID 27324708›Full record

SynthesisBMJ open2016

Prevalence of chronic pain in the UK: a systematic review and meta-analysis of population studies.

A Fayaz, P Croft, R M Langford, L J Donaldson, G T Jones

4 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 614 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
614citing papers in PubMed, 17 pooled it
72.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04274439 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effectiveness and Cost-Effectiveness of a Tele-Rehabilitation Program in the Treatment of Chronic Musculoskeletal Pain

TypeinterventionalSponsorUniversidade Cidade de Sao PauloRan2020 to 2022Enrolled160ConditionsChronic PainArmsInternet-Based Pain Education and Exercise, Online Booklet
NCT05390957 naunknown statusnot on this mapstarted 2022, after this paper: background citation

A Pilot Study of a Revised Online Chronic Pain Treatment for Military, RCMP, and Veterans

TypeinterventionalSponsorUniversity of ManitobaRan2022 to 2022Enrolled34ConditionsChronic PainArmsAcceptance Based Behavioural Therapy - Revised
NCT06138171 completednot on this mapstarted 2023, after this paper: background citation

Psychological Layers of Nociplastic Pain: Cluster Analysis of The Role of Personality Traits, Defence Mechanisms, Central Sensitization, and Childhood Traumatic Experiences in Patients With Chronic Migraine, Fibromyalgia, and Vulvodynia

TypeobservationalSponsorUniversity of Roma La SapienzaRan2023 to 2024Enrolled1,006ConditionsFibromyalgia, Chronic Migraine, Headache, VulvodyniaArmsPsychological self-reported measures assesment (questionnaire)
NCT06413277 recruitingnot on this mapstarted 2024, after this paper: background citation

Targeting the Conus Medullaris With ECAP-Controlled Closed-Loop SCS for the Treatment of Chronic Pelvic Pain: HOPE Trial

TypeobservationalSponsorAinsworth Institute of Pain ManagementRan2024 to 2027Enrolled20ConditionsChronic Pelvic Pain, Pudendal NeuralgiaArmsSaluda Evoke Smart SCS System
3 · Its place in the literature

Who cites it

614 citing papers in PubMed, 17 syntheses or guidelines pooled it, 1,326 citations in OpenAlex.

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554 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

A FayazDepartment of Surgery and Cancer, Imperial College London, London, UK.
P CroftArthritis Research UK Primary Care Centre, Keele University, Keele, Staffs, UK.
R M LangfordPain and Anaesthesia Research Centre, Barts Health NHS Trust, London, UK.
L J DonaldsonInstitute of Global Health Innovation, Imperial College London, London, UK.
G T JonesMusculoskeletal Research Collaboration (Epidemiology Group), Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
Imperial College London · GBBarts Health NHS Trust · GBKeele University · GBUniversity of Aberdeen · GB

Funding

Arthritis Research UK 18139
6 · The paper itself

Abstract

objectivesThere is little consensus regarding the burden of pain in the UK. The purpose of this review was to synthesise existing data on the prevalence of various chronic pain phenotypes in order to produce accurate and contemporary national estimates.

designMajor electronic databases were searched for articles published after 1990, reporting population-based prevalence estimates of chronic pain (pain lasting >3 months), chronic widespread pain, fibromyalgia and chronic neuropathic pain. Pooled prevalence estimates were calculated for chronic pain and chronic widespread pain.

resultsOf the 1737 articles generated through our searches, 19 studies matched our inclusion criteria, presenting data from 139 933 adult residents of the UK. The prevalence of chronic pain, derived from 7 studies, ranged from 35.0% to 51.3% (pooled estimate 43.5%, 95% CIs 38.4% to 48.6%). The prevalence of moderate-severely disabling chronic pain (Von Korff grades III/IV), based on 4 studies, ranged from 10.4% to 14.3%. 12 studies stratified chronic pain prevalence by age group, demonstrating a trend towards increasing prevalence with increasing age from 14.3% in 18-25 years old, to 62% in the over 75 age group, although the prevalence of chronic pain in young people (18-39 years old) may be as high as 30%. Reported prevalence estimates were summarised for chronic widespread pain (pooled estimate 14.2%, 95% CI 12.3% to 16.1%; 5 studies), chronic neuropathic pain (8.2% to 8.9%; 2 studies) and fibromyalgia (5.4%; 1 study). Chronic pain was more common in female than male participants, across all measured phenotypes.

conclusionsChronic pain affects between one-third and one-half of the population of the UK, corresponding to just under 28 million adults, based on data from the best available published studies. This figure is likely to increase further in line with an ageing population.

Indexed as

Age DistributionChronic PainFibromyalgiaHumansNeuralgiaPain MeasurementPrevalenceUnited KingdomEPIDEMIOLOGYPAIN MANAGEMENT

Identifiers

PMID27324708
PMCPMC4932255
OpenAlexW2464715703

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.