Evidence map›Paper›PMID 27324338›Full record

ArticleSurgical endoscopy2017

Comparison of oncological results for early- and advanced-stage thymomas: thoracoscopic thymectomy versus open thymectomy.

Makoto Odaka, Takamasa Shibasaki, Daiki Kato, Shohei Mori, Hisatoshi Asano, Makoto Yamashita, Toshiaki Morikawa

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Makoto OdakaDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan. mak@jikei.ac.jp.
Takamasa ShibasakiDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Daiki KatoDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Shohei MoriDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Hisatoshi AsanoDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Makoto YamashitaDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Toshiaki MorikawaDepartment of Surgery, Jikei University School of Medicine, 3-19-18 Nishishinbashi, Minatoku, Tokyo, 105-0003, Japan.
Jikei University School of Medicine · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluated the feasibility of thoracoscopic thymectomy (TT) for the treatment of early- and advanced-stage thymoma and compared patient outcomes with those following open thymectomy (OT).

methodsA retrospective review was conducted for 140 patients who underwent TT or OT for Masaoka stage I-IV thymoma between 1996 and 2014.

resultsTT was performed in 88 patients and OT in 52 patients. The postoperative hospital stay was significantly shorter in the TT group than in the OT group (4 and 13 days, respectively; P < 0.0001). WHO types B3-C were identified in Masaoka stage III-IV disease with high frequency. There was a significant relationship between Masaoka stage and WHO type (P < 0.05); the numbers of advanced-stage thymoma progressively increased in WHO type B3-C. Eight patients in each group had recurrent disease, with greater recurrence for WHO types B3-C and stage III-IV tumors. Five-year disease-free survival (DFS) was not different between groups (P = 0.3906); however, survival for patients with stage III-IV thymomas (47 %) was significantly worse than that for patients with stage I and II tumors (97.5 and 94.1 %, respectively; P < 0.0001). Based on multivariate analysis, both Masaoka stage and WHO type were significant predictors of thymoma patient survival.

conclusionsThese results demonstrate the safety and substantially decreased invasiveness of TT for thymoma. The oncological results were comparable between the TT and OT groups. Furthermore, Masaoka stage III-IV and WHO B3-C were revealed as independent prognostic factors for DFS.

Indexed as

AdultAgedAged, 80 and overBlood Loss, SurgicalBlood TransfusionDisease-Free SurvivalFemaleHumansLength of StayMaleMiddle AgedMultivariate AnalysisNeoplasm StagingPostoperative ComplicationsProportional Hazards ModelsRetrospective StudiesOpen thymectomyThoracoscopic thymectomyThymoma

Identifiers

PMID27324338
OpenAlexW2472610587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.