Evidence map›Paper›PMID 27324288›Full record

ArticleScientific reports2016

Study of antibacterial mechanism of graphene oxide using Raman spectroscopy.

Sitansu Sekhar Nanda, Dong Kee Yi, Kwangmeyung Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 230 citations in OpenAlex.

  1. Characterization of theInternational journal of molecular sciences · 2026
    Article
  2. Green synthesis nanocomposite GO/ZnFeScientific reports · 2026
    Article
  3. Article
  4. Synthetic Plantaricins Derived fromJournal of microbiology and biotechnology · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Graphene-Oxide Peptide-Containing Materials for Biomedical Applications.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sitansu Sekhar NandaDepartment of Chemistry, Myongji University, Yongin, 449-728, Korea.
Dong Kee YiDepartment of Chemistry, Myongji University, Yongin, 449-728, Korea.
Kwangmeyung KimKIST, Center for Theragnosis, Biomedical Research Institute, Seoul, 136791, Korea.
Myongji University · KRKorea Institute of Science and Technology · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene oxide (GO) is extensively proposed as an effective antibacterial agent in commercial product packaging and for various biomedical applications. However, the antibacterial mode of action of GO is yet hypothetical and unclear. Here we developed a new and sensitive fingerprint approach to study the antibacterial activity of GO and underlying mechanism, using Raman spectroscopy. Spectroscopic signatures obtained from biomolecules such as Adenine and proteins from bacterial cultures with different concentrations of GO, allowed us to probe the antibacterial activity of GO with its mechanism at the molecular level. Escherichia coli (E. coli) and Enterococcus faecalis (E. faecalis) were used as model micro-organisms for all the experiments performed. The observation of higher intensity Raman peaks from Adenine and proteins in GO treated E. coli and E. faecalis; correlated with induced death, confirmed by Scanning electron Microscopy (SEM) and Biological Atomic Force Microscopy (Bio-AFM). Our findings open the way for future investigations of the antibacterial properties of different nanomaterial/GO composites using Raman spectroscopy.

Indexed as

Spectrum Analysis, RamanAnti-Bacterial AgentsEnterococcus faecalisEscherichia coliGraphiteMicroscopy, Atomic ForceMicroscopy, Electron, ScanningOxidesAnti-Bacterial AgentsGraphiteOxides

Identifiers

PMID27324288
PMCPMC4914938
OpenAlexW2462937423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.