Evidence map›Paper›PMID 27324081›Full record

ArticleInfection2016

Antibiotic stewardship in a tertiary care hospital of a developing country: establishment of a system and its application in a unit-GASP Initiative.

N Shafiq, M Praveen Kumar, V Gautam, H Negi, R Roat, S Malhotra, P Ray, R Agarwal, A Bhalla, N Sharma and 6 more

Abstract read
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Article in Infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

N ShafiqDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India. nusha.pgi2302@yahoo.com.
M Praveen KumarDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
V GautamDepartment of Medical Microbiology, PGIMER, Chandigarh, 160012, India.
H NegiDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
R RoatDepartment of General Surgery, PGIMER, Chandigarh, 160012, India.
S MalhotraDepartment of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
P RayDepartment of Medical Microbiology, PGIMER, Chandigarh, 160012, India.
R AgarwalDepartment of Pulmonary Medicine, PGIMER, Chandigarh, 160012, India.
A BhallaDepartment of Internal Medicine, PGIMER, Chandigarh, 160012, India.
N SharmaDepartment of Internal Medicine, PGIMER, Chandigarh, 160012, India.
R SinghDepartment of General Surgery, PGIMER, Chandigarh, 160012, India.
G D SharmaData Center, PGIMER, Chandigarh, 160012, India.
L BahadurData Center, PGIMER, Chandigarh, 160012, India.
N YadanapudiDepartment of Anaesthesia, PGIMER, Chandigarh, 160012, India.
R GuptaDepartment of General Surgery, PGIMER, Chandigarh, 160012, India.
G SinghDepartment of General Surgery, PGIMER, Chandigarh, 160012, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDespite the proven benefits of antimicrobial stewardship, models for executing the same in the developing countries are sparse. The present study highlights the approaches undertaken by our group in initiating one such program in a public sector tertiary level health care setting of a developing country.

methodsThe study focussed on development of a system after evaluation of existing issues and case study of implementation of the program in a unit within the hospital. The system building exercise included (1) development of generic data capture form for prospective audit and feedback; (2) development of an electronic system for data capture; (3) identification of key intervention points for strategy decision for stewardship in a particular unit; (4) application of the stewardship method and (5) evaluation of outcomes.

resultsA digital system for prospective audit was constructed after a background study. In the study unit, there was a significant decline in double anaerobic coverage. There was a significant decline in the average number of antimicrobials used per patients and a decrease in Defined Daily Dose of designated antimicrobials was noted. Additionally, there was an increase in the use of optimized doses.

conclusionA system for undertaking antimicrobial stewardship with a mechanism for prospective audit was put in place. The system may be adopted by other public sector hospitals of the developing country.

Indexed as

Developing CountriesAnti-Infective AgentsDrug UtilizationDrug Utilization ReviewHospitals, PublicHumansIndiaModels, TheoreticalProspective StudiesTertiary Care CentersAnti-Infective AgentsAntibiotic stewardshipDefined daily doseDeveloping countryElectronic recordSystemTertiary care

Identifiers

PMID27324081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.