Evidence map›Paper›PMID 27323919›Full record

ReviewLancet (London, England)2016

Global health burden and needs of transgender populations: a review.

Sari L Reisner, Tonia Poteat, JoAnne Keatley, Mauro Cabral, Tampose Mothopeng, Emilia Dunham, Claire E Holland, Ryan Max, Stefan D Baral

Registry-linked trialAbstract readReview
In one paragraph

Review in Lancet (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04962997 (Health Status of Transgender Women in French Guiana and Paris), which is not on this map. Cited by 622 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
622citing papers in PubMed, 8 pooled it
116.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04962997 completednot on this mapstarted 2021, after this paper: background citation

Health Status of Transgender Women in French Guiana and Paris: a Cross-sectional View (TransGuyane)

TypeobservationalSponsorCentre Hospitalier de CayenneRan2021 to 2023Enrolled46ConditionsSexual Health, Mental HealthArmsData collection
3 · Its place in the literature

Who cites it

622 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,410 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. A systematic review of transgender male rodent model methodology.Animal models and experimental medicine · 2025
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

562 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sari L ReisnerDivision of General Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA; Fenway Institute, Fenway Health, Boston, MA, USA. Electronic address: sari.reisner@childrens.harvard.edu.
Tonia PoteatDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
JoAnne KeatleyCenter of Excellence for Transgender Health, University of California San Francisco, San Francisco, CA, USA.
Mauro CabralGlobal Action for Trans* Equality, Buenos Aires, Argentina and New York, NY, USA.
Tampose MothopengMATRIX, Lesotho, Africa.
Emilia DunhamFenway Institute, Fenway Health, Boston, MA, USA; Heller School for Social Policy and Management, Brandeis University, Waltham, MA, USA.
Claire E HollandDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Ryan MaxDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Stefan D BaralDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Johns Hopkins University · USBrandeis University · USFenway Health · USUniversity of California, San Francisco · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Bryan Lau · 2012 to 2026
$67.0M
NIAID NIH HHS P30 AI094189NIAID NIH HHS P30AI094189
6 · The paper itself

Abstract

Transgender people are a diverse population affected by a range of negative health indicators across high-income, middle-income, and low-income settings. Studies consistently document a high prevalence of adverse health outcomes in this population, including HIV and other sexually transmitted infections, mental health distress, and substance use and abuse. However, many other health areas remain understudied, population-based representative samples and longitudinal studies are few, and routine surveillance efforts for transgender population health are scarce. The absence of survey items with which to identify transgender respondents in general surveys often restricts the availability of data with which to estimate the magnitude of health inequities and characterise the population-level health of transgender people globally. Despite the limitations, there are sufficient data highlighting the unique biological, behavioural, social, and structural contextual factors surrounding health risks and resiliencies for transgender people. To mitigate these risks and foster resilience, a comprehensive approach is needed that includes gender affirmation as a public health framework, improved health systems and access to health care informed by high quality data, and effective partnerships with local transgender communities to ensure responsiveness of and cultural specificity in programming. Consideration of transgender health underscores the need to explicitly consider sex and gender pathways in epidemiological research and public health surveillance more broadly.

Indexed as

FemaleGlobal HealthHealth Services Needs and DemandHumansMaleMental DisordersMental HealthReproductive HealthSocial StigmaTransgender PersonsTranssexualism

Identifiers

PMID27323919
PMCPMC7035595
OpenAlexW2431906881

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.