ArticleScientific reports2016
Body surface area formulae: an alarming ambiguity.
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Reporting on patient's body mass index (BMI) in recent clinical trials for patients with breast cancer: a systematic review.Breast cancer research : BCR · 2024Pooled it
- Cardiac Structure and Function in Junior Athletes: A Systematic Review of Echocardiographic Studies.Reviews in cardiovascular medicine · 2022Pooled it
- Assessment of body mass-related covariates for rifampicin pharmacokinetics in healthy Caucasian volunteers.European journal of clinical pharmacology · 2024Trial
- Sex-Related Differences in Impact on Safety of Pharmacogenetic Profile for Colon Cancer Patients Treated with FOLFOX-4 or XELOX Adjuvant Chemotherapy.Scientific reports · 2019Trial
- Indexing for body surface area when assessing kidney function.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Review
- Dosing challenges for chemotherapy and immunotherapy in congenital achondroplasia: a case report and literature review.Cancer chemotherapy and pharmacology · 2026Review
- Human body surface area scales linearly with height and mass and is largely independent of body composition: a 3-D laser scanning and body composition study.American journal of physiology. Regulatory, integrative and comparative physiology · 2026Article
- An Integrated Heart Sound-Electrocardiogram Synchronization System for Early Detecting Left Ventricular Systolic Dysfunction in Pediatric Populations.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- Accuracy of Point-of-Care Transdermal GFR Methodology.Kidney international reports · 2026Article
- Predictors of ineffective platelet transfusion in surgical ICU: A retrospective study.Medicine · 2026Observational
- Short-Term 24-h Systolic Blood Pressure Variability and Subclinical Target-Organ Damage in White-Coat Hypertension: A Retrospective Cross-Sectional Study.Vascular health and risk management · 2026Article
- Association between left ventricle diastolic dysfunction and circadian blood pressure pattern in arterial hypertension.BMC cardiovascular disorders · 2025Article
- Sex differences in chemotherapy completion, toxicities, and survival in colon cancer: an analysis of 2201 patients from CALGB/SWOG 80702 (Alliance).Journal of the National Cancer Institute · 2025Article
- Determining pulmonary artery diameter on CT scans as basis for performing transthoracic echocardiography to screen for pulmonary hypertension in patients with pulmonary artery enlargement.Journal of echocardiography · 2025Article
- Validation of established thyroid ultrasound volume norms in a Chernobyl cohort.European thyroid journal · 2025Article
- Simultaneous, Seconds-Resolved Doxorubicin Measurements in the Blood and Subcutaneous Interstitial Fluid Identify Quantitative Pharmacokinetic Relationships between the Two.ACS pharmacology & translational science · 2025Article
- Review
- The Creeping Creatinine in a Growing Child With a Kidney Transplant: Distinguishing Progressive Graft Dysfunction From Normal Growth in Pediatric Kidney Transplant Recipients.Pediatric transplantation · 2025Article
- Measuring biventricular function and left atrial volume in a single five-dimensional whole-heart cardiovascular magnetic resonance scan at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025Article
- Levothyroxine dose prediction post-thyroidectomy for differentiated thyroid carcinoma.Frontiers in endocrinology · 2025Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Body surface area (BSA) plays a key role in several medical fields, including cancer chemotherapy, transplantology, burn treatment and toxicology. BSA is often a major factor in the determination of the course of treatment and drug dosage. A series of formulae to simplify the process have been developed. Because easy-to-identify, yet general, body coefficient results of those formulae vary considerably, the question arises as to whether the choice of a particular formula is valid and safe for patients. Here we show that discrepancies between most of the known BSA formulae can reach 0.5 m(2) for the standard adult physique. Although many previous studies have demonstrated that certain BSA formulae provide an almost exact fit with the patients examined, all of these studies have been performed on a limited and isolated group of people. Our analysis presents a broader perspective, considering 25 BSA formulae. The analysis revealed that the choice of a particular formula is a difficult task. Differences among calculations made by the formulae are so great that, in certain cases, they may considerably affect patients' mortality, especially for people with an abnormal physique or for children.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.