Evidence map›Paper›PMID 27322258›Full record

ReviewInternational journal of molecular sciences2016

The Potential for Microalgae as Bioreactors to Produce Pharmaceuticals.

Na Yan, Chengming Fan, Yuhong Chen, Zanmin Hu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 240 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Microalgae: revolutionizing skin repair and enhancement.Biotechnology reports (Amsterdam, Netherlands) · 2025
    Review
  6. Article
  7. EngineeringInternational journal of molecular sciences · 2025
    Review
  8. Review
  9. Review
  10. Engineering the Novel Extremophile AlgaACS ES&T engineering · 2025
    Article
  11. Flocculation ofWater science and technology : a journal of the International Association on Water Pollution Research · 2024
    Article
  12. The red algaProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Review
  14. Article
  15. Dietary Supplementation ofAntioxidants (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Review
  18. Extraction of Valuable Biomolecules from the MicroalgaMolecules (Basel, Switzerland) · 2023
    Review
  19. Molecules (Basel, Switzerland) · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Na YanInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. yanna19881204@163.com.
Chengming FanInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. cmfan@genetics.ac.cn.
Yuhong ChenInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. yhchen@genetics.ac.cn.
Zanmin HuInstitute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China. zmhu@genetics.ac.cn.
Institute of Genetics and Developmental Biology · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As photosynthetic organisms, microalgae can efficiently convert solar energy into biomass. Microalgae are currently used as an important source of valuable natural biologically active molecules, such as carotenoids, chlorophyll, long-chain polyunsaturated fatty acids, phycobiliproteins, carotenoids and enzymes. Significant advances have been achieved in microalgae biotechnology over the last decade, and the use of microalgae as bioreactors for expressing recombinant proteins is receiving increased interest. Compared with the bioreactor systems that are currently in use, microalgae may be an attractive alternative for the production of pharmaceuticals, recombinant proteins and other valuable products. Products synthesized via the genetic engineering of microalgae include vaccines, antibodies, enzymes, blood-clotting factors, immune regulators, growth factors, hormones, and other valuable products, such as the anticancer agent Taxol. In this paper, we briefly compare the currently used bioreactor systems, summarize the progress in genetic engineering of microalgae, and discuss the potential for microalgae as bioreactors to produce pharmaceuticals.

Indexed as

BioreactorsGenetic EngineeringIndustrial MicrobiologyMicroalgaeRecombinant ProteinsRecombinant Proteinsbioreactormicroalgaepharmaceuticalsrecombinant proteins

Identifiers

PMID27322258
PMCPMC4926494
OpenAlexW2434905294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.