Evidence map›Paper›PMID 27322032›Full record

ReviewFuture cardiology2016

Positron emission tomography imaging of coronary atherosclerosis.

Alastair J Moss, Philip D Adamson, David E Newby, Marc R Dweck

Abstract readReview
In one paragraph

Review in Future cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. PET Imaging of Cardiac Hypoxia: Hitting Hypoxia Where It Hurts.Current cardiovascular imaging reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alastair J MossCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Philip D AdamsonCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
David E NewbyCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Marc R DweckCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.

Funding

British Heart Foundation CH/09/002British Heart Foundation FS/13/77/30488British Heart Foundation FS/14/78/31020Medical Research Council G0701127Wellcome TrustWellcome Trust WT103782AIA
6 · The paper itself

Abstract

Inflammation has a central role in the progression of coronary atherosclerosis. Recent developments in cardiovascular imaging with the advent of hybrid positron emission tomography have provided a window into the molecular pathophysiology underlying coronary plaque inflammation. Using novel radiotracers targeted at specific cellular pathways, the potential exists to observe inflammation, apoptosis, cellular hypoxia, microcalcification and angiogenesis in vivo. Several clinical studies are now underway assessing the ability of this hybrid imaging modality to inform about atherosclerotic disease activity and the prediction of future cardiovascular risk. A better understanding of the molecular mechanisms governing coronary atherosclerosis may be the first step toward offering patients a more stratified, personalized approach to treatment.

Indexed as

Positron-Emission TomographyAtherosclerosisCoronary Artery DiseaseHumansRisk Factorsatherosclerosiscardiac imagingpersonalized medicine

Identifiers

PMID27322032
PMCPMC4926532

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.