Evidence map›Paper›PMID 27320081›Full record

ArticleScientific reports2016

Isolation and characterization of a bacteriophage phiEap-2 infecting multidrug resistant Enterobacter aerogenes.

Erna Li, Xiao Wei, Yanyan Ma, Zhe Yin, Huan Li, Weishi Lin, Xuesong Wang, Chao Li, Zhiqiang Shen, Ruixiang Zhao and 5 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 56 citations in OpenAlex.

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  15. Two Newly IsolatedViruses · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Erna LiCollege of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Xiao WeiInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Yanyan MaCollege of Food Science, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Zhe YinState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Huan LiInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Weishi LinInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Xuesong WangInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Chao LiKey Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, 300050, China.
Zhiqiang ShenKey Laboratory of Risk Assessment and Control for Environment and Food Safety, Tianjin Institute of Health and Environmental Medicine, Tianjin, 300050, China.
Ruixiang ZhaoCollege of Food Science, Henan Institute of Science and Technology, Xinxiang, 453003, China.
Huiying YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Aimin JiangCollege of Food Science, South China Agricultural University, Guangzhou, 510642, China.
Wenhui YangState Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
Jing YuanInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Xiangna ZhaoInstitute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, 100071, China.
Academy of Military Medical Sciences · CNInstitute of Microbiology · CNHenan Institute of Science and Technology · CNSouth China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enterobacter aerogenes (Enterobacteriaceae) is an important opportunistic pathogen that causes hospital-acquired pneumonia, bacteremia, and urinary tract infections. Recently, multidrug-resistant E. aerogenes have been a public health problem. To develop an effective antimicrobial agent, bacteriophage phiEap-2 was isolated from sewage and its genome was sequenced because of its ability to lyse the multidrug-resistant clinical E. aerogenes strain 3-SP. Morphological observations suggested that the phage belongs to the Siphoviridae family. Comparative genome analysis revealed that phage phiEap-2 is related to the Salmonella phage FSL SP-031 (KC139518). All of the structural gene products (except capsid protein) encoded by phiEap-2 had orthologous gene products in FSL SP-031 and Serratia phage Eta (KC460990). Here, we report the complete genome sequence of phiEap-2 and major findings from the genomic analysis. Knowledge of this phage might be helpful for developing therapeutic strategies against E. aerogenes.

Indexed as

Drug Resistance, Multiple, BacterialAnti-Bacterial AgentsBacteriophagesCell WallCluster AnalysisCross InfectionDNADNA, ViralEnterobacter aerogenesGenome, ViralHumansHydrogen-Ion ConcentrationMicroscopy, ElectronPhenotypePhylogenySewageAnti-Bacterial AgentsDNADNA, ViralSewage

Identifiers

PMID27320081
PMCPMC4913238
OpenAlexW4240747820

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.