Evidence map›Paper›PMID 27319745›Full record

Observational studyJournal of atherosclerosis and thrombosis2017

Anticoagulation Stability Depends on CHADS

Keita Odashiro, Taku Yokoyama, Mitsuhiro Fukata, Takeshi Arita, Toru Maruyama, Koichi Akashi

Open access · diamondAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Journal of atherosclerosis and thrombosis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Factors Affecting the Time in Therapeutic Range of Warfarin Anticoagulation Therapy in Patients with Atrial Fibrillation.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Keita OdashiroDepartment of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences.
Taku Yokoyama
Mitsuhiro Fukata
Takeshi Arita
Toru Maruyama
Koichi Akashi
Kyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimAlthough warfarin remains important despite the widespread use of nonvitamin K antagonist oral anticoagulants (NOACs), to date, the reality of warfarin use in the "NOACs era" is unclear. This multicenter observational study aimed to clarify the key factors contributing to warfarin treatment stability.

methodsThe practical use of warfarin, stability of warfarin therapy, and factors contributing to this stability were investigated in community-based hospitals through a real-world study. Clinical data were retrospectively extracted from the medical records of warfarin-treated Japanese patients (age, 71.3±5.5 years) with atrial fibrillation (AF), prosthetic heart valve, or other concerns requiring anticoagulation. Treatment stability was considered as time in therapeutic range of international normalized ratio of prothrombin time (TTR: %). The factors contributing to TTR were investigated, including CHADS

resultsMean CHADS

conclusionsThis retrospective study demonstrated that the CHADS

Indexed as

AgedAged, 80 and overAnticoagulantsAtrial FibrillationBiomarkersBlood CoagulationCardiovascular DiseasesEchocardiographyFemaleHepatorenal SyndromeHumansKidney Function TestsLiver Function TestsMagnetic Resonance ImagingMaleMiddle AgedAnticoagulantsBiomarkersWarfarin

Identifiers

PMID27319745
PMCPMC5225134
OpenAlexW2432509778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.