Evidence map›Paper›PMID 27319430›Full record

ArticlePsychology, health & medicine2017

Body mass index, inflammatory biomarkers and neurocognitive impairment in HIV-infected persons.

Chukwuemeka N Okafor, Natalie E Kelso, Vaughn Bryant, Larry E Burrell, Maria Jose Míguez, Assawin Gongvatana, Karen T Tashima, Suzanne de la Monte, Robert L Cook, Ronald A Cohen

Open access · greenAbstract read
In one paragraph

Article in Psychology, health & medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. The CD8Microbiology and molecular biology reviews : MMBR · 2021
    Review
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  8. Article
  9. Observational
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  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Chukwuemeka N Okafora Department of Epidemiology, College of Public Health and Health Professions, College of Medicine , University of Florida , Gainesville , FL , USA.
Natalie E Kelsoa Department of Epidemiology, College of Public Health and Health Professions, College of Medicine , University of Florida , Gainesville , FL , USA.
Vaughn Bryantb Department of Clinical and Health Psychology, College of Public Health and Health Professions , University of Florida , Gainesville , FL , USA.
Larry E Burrellb Department of Clinical and Health Psychology, College of Public Health and Health Professions , University of Florida , Gainesville , FL , USA.
Maria Jose Míguezc School of Integrated Science and Humanity (SISH) , Florida International University , Miami , FL , USA.
Assawin Gongvatanad Department of Psychiatry , University of California San Diego , San Diego , CA , USA.
Karen T Tashimae Departments of Medicine and Pathology , Warren Alpert Medical School of Brown University , Providence , RI , USA.
Suzanne de la Montee Departments of Medicine and Pathology , Warren Alpert Medical School of Brown University , Providence , RI , USA.
Robert L Cooka Department of Epidemiology, College of Public Health and Health Professions, College of Medicine , University of Florida , Gainesville , FL , USA.
Ronald A Cohenf Center for Cognitive Aging and Memory, Institute on Aging, and the Departments of Neurology, Psychiatry, and Aging and Geriatric Research , University of Florida , Gainesville , FL , USA.
Brown University · USFlorida College · USUniversity of Florida · USUniversity of Florida Health · USFlorida International University · USUniversity of California, San Diego · US

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH · 1998 to 2026
$51.7M
Virology CoreP01AA019072 · NIAAA · BROWN UNIVERSITY · PI WRAY, TYLER BLAKE · 2010 to 2024
$19.7M
Southern HIV and Alcohol Research Consortium Administrative and Research Support CoreU24AA022002 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2012 to 2022
$5.5M
WISE II - Obesity and Type-2 Diabetes: Bariatric Surgery Effects on Brain FunctionR01DK099334 · NIDDK · UNIVERSITY OF FLORIDA · PI RONALD A COHEN, Eric Porges · 2014 to 2026
$4.6M
Age Effects on HIV-associated Brain DysfunctionR01MH074368 · NIMH · MIRIAM HOSPITAL · PI COHEN, RONALD A · 2006 to 2010
$1.7M
Working memory: a critical factor underlying alcohol reduction intervention responseF31AA024060 · NIAAA · UNIVERSITY OF FLORIDA · PI BRYANT, VAUGHN E · 2015 to 2017
$115k
Alcohol Consumption Patterns on Cardiovascular Health in Persons Living with HIVF31AA024064 · NIAAA · UNIVERSITY OF FLORIDA · PI CHICHETTO, NATALIE E · 2015 to 2016
$69k
The impact of long-term marijuana use on the neurocognitive functioning of individuals living with HIVF31DA039810 · NIDA · UNIVERSITY OF FLORIDA · PI OKAFOR, CHUKWUEMEKA NKEMAKONAM · 2015 to 2016
$60k
NIAAA NIH HHS F31 AA024060NIAAA NIH HHS F31 AA024064NIAAA NIH HHS P01 AA019072NIAAA NIH HHS U24 AA022002NIAID NIH HHS P30 AI042853NIDA NIH HHS F31 DA039810NIDDK NIH HHS R01 DK099334NIMH NIH HHS R01 MH074368
6 · The paper itself

Abstract

To determine the relationships among body mass index (BMI), and HIV-associated neurocognitive impairment and the potential mediating effects of inflammatory cytokines. Among the HIV-infected individuals (N = 90) included in this study, obesity was associated with slower processing speed (β = -.229, standard error (SE) = 2.15, p = .033), compared to participants with a normal BMI, after controlling for psychosocial and HIV clinical factors. Serum concentrations of the interleukin-16 (IL-16) cytokine were significantly associated with slowed processing speed (β = -.235, SE = 1.62, p = .033) but did not mediate the relationship between obesity and processing speed These findings suggest that obesity may contribute to cognitive processing speed deficits in HIV-infected adults. Elevated concentrations of IL-16 are also associated with slowing, though the results suggest that obesity and IL-16 may exert independent effects.

Indexed as

Body Mass IndexCognition DisordersAdultBiomarkersCytokinesFemaleHIV InfectionsHumansInterleukinsMaleMiddle AgedObesityBiomarkersCytokinesInterleukinsbody mass indexcytokinesHIVinflammationneurocognition

Identifiers

PMID27319430
PMCPMC5173436
OpenAlexW2468324764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.