Evidence map›Paper›PMID 27318820›Full record

ArticleInternational urology and nephrology2016

Clinical characteristics and outcomes of HIV-seropositive men treated with surgery for prostate cancer.

Sudeh Izadmehr, Michael Leapman, Adele R Hobbs, Maria Katsigeorgis, Fatima Nabizada-Pace, Seyed Behzad Jazayeri, David B Samadi

Erratum issuedAbstract read
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In one paragraph

Article in International urology and nephrology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Prostate cancer in people with HIV.Current opinion in infectious diseases · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sudeh IzadmehrDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Michael LeapmanDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Adele R HobbsDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Maria KatsigeorgisDepartment of Urology, Hofstra Northwell School of Medicine, Lenox Hill Hospital, 485 Madison Avenue, 21 Floor, New York, NY, 10022, USA.
Fatima Nabizada-PaceDepartment of Urology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Seyed Behzad JazayeriDepartment of Urology, Hofstra Northwell School of Medicine, Lenox Hill Hospital, 485 Madison Avenue, 21 Floor, New York, NY, 10022, USA.
David B SamadiDepartment of Urology, Hofstra Northwell School of Medicine, Lenox Hill Hospital, 485 Madison Avenue, 21 Floor, New York, NY, 10022, USA. robotmd@yahoo.com.
Icahn School of Medicine at Mount Sinai · USLenox Hill Hospital · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe natural history and optimal management strategy for men with human immunodeficiency virus (HIV) and prostate cancer remain to be definitively characterized. This study was conducted to evaluate the clinical characteristics and outcomes of HIV-seropositive men treated with robotic-assisted radical laparoscopic prostatectomy for localized prostate cancer.

methodsAfter Institutional Review Board approval, a prospective database of 2175 operative cases of clinically localized prostate adenocarcinoma was reviewed. Thirteen patients were identified as HIV-positive. Tumor characteristics, operative outcomes, postoperative outcomes, histology (Gleason score), local invasion, biochemical recurrence, and surgical complications were compared with HIV-negative patients.

resultsThere were no preoperative demographic differences between the HIV-positive and HIV-negative patients. HIV-positive patients had higher prostate specific antigen (PSA) levels at time of diagnosis which was not statistically significant. However, HIV-positive patients had higher D'Amico risk assessment (p < 0.05). There was no postoperative complication. HIV-positive patients treated with robotic prostatectomy had similarly favorable perioperative and short-term biochemical recurrence-free survival outcomes.

conclusionOur findings show that minimally invasive prostatectomy can be safely considered as a therapeutic option in otherwise eligible HIV-positive patients with clinically significant prostate cancer. Further research is necessary to outline a diagnostic and treatment guideline for HIV-positive men in detection and treatment of prostate cancer.

Indexed as

AdenocarcinomaProstatectomyProstatic NeoplasmsAgedDisease-Free SurvivalHIV SeropositivityHumansLaparoscopyMaleMiddle AgedNeoplasm GradingNeoplasm StagingOutcome and Process Assessment, Health CareProstateRisk AssessmentRobotic Surgical ProceduresHIVProstate cancerProstate-specific antigenRobotic-assisted laparoscopic radical prostatectomy

Identifiers

PMID27318820
OpenAlexW4237409144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.