Evidence map›Paper›PMID 27318740›Full record

ReviewMedical principles and practice : international journal of the Kuwait University, Health Science Centre

Advantages and Limitations of Focal Liver Lesion Assessment with Ultrasound Contrast Agents: Comments on the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Guidelines.

Liliana Chiorean, Claudio Tana, Barbara Braden, Cosmin Caraiani, Zeno Sparchez, Xin-Wu Cui, Ulrich Baum, Christoph F Dietrich

Abstract readReview
In one paragraph

Review in Medical principles and practice : international journal of the Kuwait University, Health Science Centre. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Contrast-enhanced ultrasound quantitative parameters for predicting benign and malignant greater omentum lesions: an applied study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Ultrasound—New Techniques Are Extending the Applications.Deutsches Arzteblatt international · 2023
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Intraoperative Imaging Techniques to Visualize Hepatic (Micro)Perfusion: An Overview.European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes · 2020
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Liliana ChioreanDepartment of Internal Medicine, Caritas Hospital, Bad Mergentheim, Germany.
Claudio Tana
Barbara Braden
Cosmin Caraiani
Zeno Sparchez
Xin-Wu Cui
Ulrich Baum
Christoph F Dietrich

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-enhanced ultrasound (CEUS) represents a significant breakthrough in sonography. Due to US contrast agents (UCAs) and contrast-specific techniques, sonography offers the potential to show enhancement of liver lesions in a similar way as contrast-enhanced cross-sectional imaging techniques. The real-time assessment of liver perfusion throughout the vascular phases, without any risk of nephrotoxicity, represents one of the major advantages that this technique offers. CEUS has led to a dramatic improvement in the diagnostic accuracy of US and subsequently has been included in current guidelines as an important step in the diagnostic workup of focal liver lesions (FLLs), resulting in a better patient management and cost-effective therapy. The purpose of this review was to provide a detailed description of contrast agents used in different cross-sectional imaging procedures for the study of FLLs, focusing on characteristics, indications and advantages of UCAs in clinical practice.

Indexed as

Administration, IntravenousContrast MediaHumansLiver DiseasesMagnetic Resonance ImagingTomography, X-Ray ComputedUltrasonographyContrast Media

Identifiers

PMID27318740
PMCPMC5588445

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.