Evidence map›Paper›PMID 27318672›Full record

ArticleThe Journal of membrane biology2016

A Microdosimetric Study of Electropulsation on Multiple Realistically Shaped Cells: Effect of Neighbours.

Agnese Denzi, Francesca Camera, Caterina Merla, Barbara Benassi, Claudia Consales, Alessandra Paffi, Francesca Apollonio, Micaela Liberti

Abstract read
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In one paragraph

Article in The Journal of membrane biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biophysical principles of pulsed field ablation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agnese DenziCenter for Life Nano Science at Sapienza, Istituto Italiano di Tecnologia, Rome, Italy.
Francesca CameraDepartment of Information Engineering, Electronics and Telecommunication (DIET), Italian Inter-University Centre of Electromagnetic Fields and Bio-Systems (ICEmB), University of Rome "La Sapienza", 00184, Rome, Italy.
Caterina MerlaDivision of Health Protection Technologies, ENEA-Italian National Agency for New Technologies, Energy and Sustainable Economic Development, 00123, Rome, Italy.
Barbara BenassiDivision of Health Protection Technologies, ENEA-Italian National Agency for New Technologies, Energy and Sustainable Economic Development, 00123, Rome, Italy.
Claudia ConsalesDivision of Health Protection Technologies, ENEA-Italian National Agency for New Technologies, Energy and Sustainable Economic Development, 00123, Rome, Italy.
Alessandra PaffiDepartment of Information Engineering, Electronics and Telecommunication (DIET), Italian Inter-University Centre of Electromagnetic Fields and Bio-Systems (ICEmB), University of Rome "La Sapienza", 00184, Rome, Italy.
Francesca ApollonioDepartment of Information Engineering, Electronics and Telecommunication (DIET), Italian Inter-University Centre of Electromagnetic Fields and Bio-Systems (ICEmB), University of Rome "La Sapienza", 00184, Rome, Italy.
Micaela LibertiDepartment of Information Engineering, Electronics and Telecommunication (DIET), Italian Inter-University Centre of Electromagnetic Fields and Bio-Systems (ICEmB), University of Rome "La Sapienza", 00184, Rome, Italy. liberti@diet.uniroma1.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past decades, the effects of ultrashort-pulsed electric fields have been used to investigate their action in many medical applications (e.g. cancer, gene electrotransfer, drug delivery, electrofusion). Promising aspects of these pulses has led to several in vitro and in vivo experiments to clarify their action. Since the basic mechanisms of these pulses have not yet been fully clarified, scientific interest has focused on the development of numerical models at different levels of complexity: atomic (molecular dynamic simulations), microscopic (microdosimetry) and macroscopic (dosimetry). The aim of this work is to demonstrate that, in order to predict results at the cellular level, an accurate microdosimetry model is needed using a realistic cell shape, and with their position and packaging (cell density) characterised inside the medium.

Indexed as

Models, BiologicalCell Line, TumorCell MembraneCell ShapeElectroporationHumansModels, TheoreticalElectroporationMesodosimetryMicrodosimetryNanosecond and microsecond pulsed electric fieldsShielding effect

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.