ArticleJournal of cancer research and clinical oncology2016
Endometrial and cervical cancer patients with multiple sentinel lymph nodes at laparoscopic ICG mapping: How many are enough?
Article in Journal of cancer research and clinical oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Sentinel node biopsy for diagnosis of lymph node involvement in endometrial cancer.The Cochrane database of systematic reviews · 2021Pooled it
- Additional Value of FDG-PET/MRI Complementary to Sentinel Lymphonodectomy for Minimal Invasive Lymph Node Staging in Patients with Endometrial Cancer: A Prospective Study.Diagnostics (Basel, Switzerland) · 2024Article
- Comparison of Different Near-Infrared Technologies to Detect Sentinel Lymph Node in Uterine Cancer: A Prospective Comparative Cohort Study.International journal of environmental research and public health · 2022Observational
- Exploratory Study of the Clinical Value of Near-Infrared Sentinel Lymph Node Mapping With Indocyanine Green in Vulvar Cancer Patients.Frontiers in oncology · 2021Article
- Sentinel lymph node intraoperative analysis in endometrial cancer.Journal of cancer research and clinical oncology · 2020Article
- Surgical staging in endometrial cancer.Journal of cancer research and clinical oncology · 2019Review
- The impact of different doses of indocyanine green on the sentinel lymph-node mapping in early stage endometrial cancer.Journal of cancer research and clinical oncology · 2018Article
- Identification of the Thoracic Duct Using Indocyanine Green During Cervical Lymphadenectomy.Annals of surgical oncology · 2018Article
- Retrospective validation of the laparoscopic ICG SLN mapping in patients with grade 3 endometrial cancer.Journal of cancer research and clinical oncology · 2018Article
- The combination of preoperative PET/CT and sentinel lymph node biopsy in the surgical management of early-stage cervical cancer.Journal of cancer research and clinical oncology · 2017Article
- Sentinel lymph node mapping in endometrial cancer: comparison of fluorescence dye with traditional radiocolloid and blue.Journal of cancer research and clinical oncology · 2017Review
- New procedures for the identification of sentinel lymph node: shaping the horizon of future management in early stage uterine cervical cancer.Updates in surgery · 2017Review
- FIGO stage IIIC endometrial cancer identification among patients with complex atypical hyperplasia, grade 1 and 2 endometrioid endometrial cancer: laparoscopic indocyanine green sentinel lymph node mapping versus frozen section of the uterus, why get around the problem?Journal of cancer research and clinical oncology · 2017Article
- The impact of examined lymph node count on survival in squamous cell carcinoma and adenocarcinoma of the uterine cervix.Cancer management and research · 2017Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe adoption of a sentinel lymph node (SLN) algorithm and the presence of high bilateral detection rates have been associated with increased accuracy of SLN mapping in cervical and endometrial cancer patients. In this context, the significance of the number of SLNs removed has not yet been investigated. The aim of this study was to evaluate (a) whether or not a higher SLN removal count is associated with a reduced false-negative rate and (b) which clinical factors correlate with the number of SLNs removed.
methodsPatients with cervical or endometrial cancer who underwent SLN mapping with bilateral SLN detection followed by lymphadenectomy were evaluated retrospectively. On the basis of the mean number of the SLNs removed, the patients were divided in two groups: Group 1 included patients with up to 3 SLNs removed and Group 2 included patients with more than 3 SLNs removed. Factors predicting a higher SLN count were evaluated using univariate and multivariate analysis.
resultsEighty-four patients met the inclusion criteria. The two groups consisted of 42 patients each and differed only by the median SLN count. Two endometrial cancer patients in Group 1 had false-negative pelvic SLNs and isolated para-aortic metastases; no false-negative SLNs were recorded in Group 2 (p = n.s.). The results of multivariate analysis indicted that the number of SLNs removed was influenced only in cases where the operating surgeon had performed more than 20 laparoscopic ICG SLN mappings.
conclusionsA higher SLN count does not seem to increase the accuracy of SLN mapping in cervical and endometrial cancer patients.
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