Evidence map›Paper›PMID 27318475›Full record

ReviewGlycoconjugate journal2017

Changes of glycoconjugate expression profiles during early development.

Kazuko Handa, Sen-Itiroh Hakomori

Abstract readReview
PubMed Publisher
In one paragraph

Review in Glycoconjugate journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

  1. Tumor-Associated Glycan Exploits Adenosine Receptor 2A Signaling to Facilitate Immune Evasion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
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  11. Expression of Fucosyltransferase 4 (Journal of clinical medicine · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kazuko HandaDivision of Biomembrane Research, Pacific Northwest Research Institute, 720 Broadway, Seattle, WA, 98112, USA.
Sen-Itiroh HakomoriDivision of Biomembrane Research, Pacific Northwest Research Institute, 720 Broadway, Seattle, WA, 98112, USA. hakomori@u.washington.edu.
Pacific Northwest Diabetes Research Institute · US

Funding

The Biomembrane Institute N/A
6 · The paper itself

Abstract

A variety of glycoconjugates, including glycosphingolipids (GSLs), expressed in mammalian tissues and cells were isolated and characterized in early biochemical studies. Later studies of virus-transformed fibroblasts demonstrated the association of GSL expression profiles with cell phenotypes. Changes of GSL expression profile were observed during mammalian embryogenesis. Cell surface molecules expressed on embryos in a stage-specific manner appeared to play key roles in regulation of cell-cell interaction and cell sorting during early development. Many mAbs showing stage-specific reactivity with mouse embryos were shown to recognize carbohydrate epitopes. Among various stage-specific embryonic antigens (SSEAs), SSEA-1 was found to react with neolacto-series GSL Le

Indexed as

Embryonic DevelopmentAnimalsEmbryonic Stem CellsGlycosphingolipidsHumansStage-Specific Embryonic AntigensGlycosphingolipidsStage-Specific Embryonic AntigensEmbryogenesisEmbryonal carcinomaEmbryonic stem cellGlycoconjugateGlycosphingolipidStage-specific embryonic antigen

Identifiers

PMID27318475
OpenAlexW2421745071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.