Evidence map›Paper›PMID 27318375›Full record

ArticleThe Journal of pediatrics2016

Sex Differences in the Relationship between Fitness and Obesity on Risk for Asthma in Adolescents.

Kim D Lu, John Billimek, Ronen Bar-Yoseph, Shlomit Radom-Aizik, Dan M Cooper, Hoda Anton-Culver

Abstract readComparative Study
In one paragraph

Article in The Journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Obesity-related asthma in children and adolescents.The Lancet. Child & adolescent health · 2022
    Review
  4. Article
  5. Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Review
  6. Asthma interactions between obesity and other risk factors.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  7. Self-Reported Physical Activity and Asthma Risk in Children.The journal of allergy and clinical immunology. In practice · 2022
    Article
  8. The bidirectional association between wheezing and obesity during adolescence and the beginning of adulthood in the 1993 birth cohort, Pelotas, Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Evidence for lifestyle interventions in asthma.Breathe (Sheffield, England) · 2019
    Review
  15. Short-term effects of particle size fractions on lung function of late adolescents.Environmental science and pollution research international · 2018
    Article
  16. Article
  17. Review
  18. Obesity and asthma.The Journal of allergy and clinical immunology · 2018
    Review
  19. Prevalence of asthma and associated factors among male late adolescents in Tabriz, Iran.Environmental science and pollution research international · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kim D LuDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, CA. Electronic address: kdlu@uci.edu.
John BillimekHealth Policy Research Institute and Division of General Internal Medicine, School of Medicine, University of California, Irvine, CA.
Ronen Bar-YosephDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, CA.
Shlomit Radom-AizikDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, CA.
Dan M CooperDepartment of Pediatrics and Pediatric Exercise and Genomics Research Center, University of California, Irvine, CA.
Hoda Anton-CulverDepartment of Epidemiology, University of California, Irvine, CA.
University of California, Irvine · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Peripheral Blood Mononuclear Cells, Exercise, and Children: Initial MechanismsP01HD048721 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, RADOM-AIZIK, SHLOMIT · 2006 to 2016
$13.6M
Transforming Exercise Testing and Physical Activity Assessment in Children: New Approaches to Advance Clinical Translational Research in Child HealthU01TR002004 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, RADOM-AIZIK, SHLOMIT · 2018 to 2022
$6.5M
NCATS NIH HHS U01 TR002004NCATS NIH HHS UL1 TR001414NICHD NIH HHS P01 HD048721
6 · The paper itself

Abstract

objectiveTo evaluate the relationship of fitness and obesity on asthma risk in adolescent girls and boys. STUDY

designA cross-sectional assessment of participants 12-19 years of age was conducted by the use of data from the 1999-2004 National Health and Nutrition Examination Survey. Participants completed cardiorespiratory fitness testing, body composition measurements, and respiratory questionnaires.

resultsA total of 4828 participants were included. Overweight/obesity was associated with increased odds of history of asthma (aOR 1.63, 95% CI 1.16-2.30), current asthma (aOR 1.73, 95% CI 1.13, 2.64), and wheezing (aOR 1.40, 95% CI 1.03-1.91) in girls. Overweight/obesity also was associated with increased odds of asthma attacks (aOR 2.67, 95% CI 1.56-4.65) and wheezing related to exercise (aOR 1.60, 95% CI 1.07-2.38) in girls. High fitness was associated with lower odds of asthma-related visits to the emergency department (aOR 0.24, 95% CI 0.07-0.89), wheezing-related medical visits (aOR 0.31, 95% CI 0.13-0.75), wheezing-related missed days (aOR 0.14, 95% CI 0.06-0.33), and wheezing related to exercise (aOR 0.43, 95% CI 0.24-0.76) in boys.

conclusionOverweight/obesity is associated with increased asthma prevalence and morbidity in girls but not in boys, independent of fitness. High fitness is associated with decreased rates of asthma morbidity in boys but not in girls, independent of weight status. Obesity and fitness may each influence asthma onset and severity in different ways for girls compared with boys.

Indexed as

Physical FitnessAdolescentAsthmaChildCross-Sectional StudiesFemaleHumansMalePediatric ObesityPrevalenceRisk AssessmentSex DistributionSex FactorsYoung Adultadolescentsasthmafitnessobesity

Identifiers

PMID27318375
PMCPMC5003726
OpenAlexW2428576375

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.