ArticleNeurobiology of aging2016
Reconfiguration of brain network architecture to support executive control in aging.
Article in Neurobiology of aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large-scale resting-state functional brain networks in aging.Psychophysiology · 2023Pooled it
- Modular Brain Network Organization Predicts Response to Cognitive Training in Older Adults.PloS one · 2016Trial
- Shared white matter connectome-based correlates of self-reproach, response failure, spatial planning, and resilience in patients with subthreshold depression: a graph theory approach.Scientific reports · 2026Article
- Functional reconfiguration between rest and movie watching relates to theory-of-mind performance among young and older adults.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Variation in brain aging: A review and perspective on the utility of individualized approaches to the study of functional networks in aging.Neurobiology of aging · 2025Review
- Tangent space functional reconfigurations in individuals at risk for alcohol use disorder.Network neuroscience (Cambridge, Mass.) · 2025Article
- Age-related differences in resting-state, task-related, and structural brain connectivity: graph theoretical analyses and visual search performance.Brain structure & function · 2024Article
- Edge-Community Entropy Is a Novel Neural Correlate of Aging and Moderator of Fluid Cognition.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Age-related reorganization of functional network architecture in semantic cognition.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Cooperation and competition between the default mode network and frontal parietal network in the elderly.Frontiers in psychology · 2023Article
- Influence of goals on modular brain network organization during working memory.Frontiers in behavioral neuroscience · 2023Article
- Getting Fit to Counteract Cognitive Aging: Evidence and Future Directions.Physiology (Bethesda, Md.) · 2022Review
- Neurological Music Therapy Rebuilds Structural Connectome after Traumatic Brain Injury: Secondary Analysis from a Randomized Controlled Trial.Journal of clinical medicine · 2022Article
- Functional brain rewiring and altered cortical stability in ulcerative colitis.Molecular psychiatry · 2022Article
- Age-Dependent Contribution of Domain-General Networks to Semantic Cognition.Cerebral cortex (New York, N.Y. : 1991) · 2022Article
- A survey of brain network analysis by electroencephalographic signals.Cognitive neurodynamics · 2022Article
- Neural alterations in opioid-exposed infants revealed by edge-centric brain functional networks.Brain communications · 2022Article
- Posterior brain sensorimotor recruitment for inhibition of delayed responses in children.Experimental brain research · 2021Article
- The effect of vascular health factors on white matter microstructure mediates age-related differences in executive function performance.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Age differences in functional network reconfiguration with working memory training.Human brain mapping · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Aging is accompanied by declines in executive control abilities and changes in underlying brain network architecture. Here, we examined brain networks in young and older adults during a task-free resting state and an N-back task and investigated age-related changes in the modular network organization of the brain. Compared with young adults, older adults showed larger changes in network organization between resting state and task. Although young adults exhibited increased connectivity between lateral frontal regions and other network modules during the most difficult task condition, older adults also exhibited this pattern of increased connectivity during less-demanding task conditions. Moreover, the increase in between-module connectivity in older adults was related to faster task performance and greater fractional anisotropy of the superior longitudinal fasciculus. These results demonstrate that older adults who exhibit more pronounced network changes between a resting state and task have better executive control performance and greater structural connectivity of a core frontal-posterior white matter pathway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.