Evidence map›Paper›PMID 27317963›Full record

ArticleAddiction (Abingdon, England)2016

Adolescent cannabis use and repeated voluntary unprotected sex in women.

Arpana Agrawal, Lauren Few, Elliot C Nelson, Arielle Deutsch, Julia D Grant, Kathleen K Bucholz, Pamela A F Madden, Andrew C Heath, Michael T Lynskey

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Addiction (Abingdon, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Investigating the Relative Influence of Romantic Sex Partners and Close Friends on Adolescent Alcohol and Marijuana Use.Prevention science : the official journal of the Society for Prevention Research · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arpana AgrawalWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA. arpana@wustl.edu.
Lauren FewWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Elliot C NelsonWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Arielle DeutschUniversity of Missouri-Columbia, Department of Psychological Sciences, Columbia, MO, USA.
Julia D GrantWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Kathleen K BucholzWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Pamela A F MaddenWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Andrew C HeathWashington University School of Medicine, Department of Psychiatry, Saint Louis, MO, USA.
Michael T LynskeyKing's College, Institute of Psychiatry, Psychology and Neuroscience, Addictions Department, London, UK.

Funding

PILOT--GENETIC EPIDEMIOLOGY OF ALCOHOL AND TOBACCO CONSUMPTION IN CHINESE SAMPLEP50AA011998 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 1999 to 2008
$12.6M
Dual Processes in HIV Risk Behavior in Drug AbusersR01DA023368 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI STACY, ALAN W · 2008 to 2012
$3.2M
ALCOHOL USE DISORDER IN YOUNG WOMEN: GENETIC EPIDEMIOLOGY: MOAFTS WAVE 7R01AA017915 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2009 to 2013
$3.2M
GxE in Early Childhood: Twin MothersR01HD049024 · NICHD · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2005 to 2009
$2.9M
CANNABIS AND TOBACCO INVOLVEMENT: A TWIN STUDYR01DA023668 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2007 to 2016
$2.5M
GENE-ENVIRONMENT INTERPLAY IN ALCOHOLISMK05AA017688 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C. · 2008 to 2017
$1.9M
NEIGHBORHOOD, FAMILY AND INDIVIDUAL FACTORS IN ADOLESCENT DRINKINGR01AA021492 · NIAAA · WASHINGTON UNIVERSITY · PI HEATH, ANDREW C., SCHOOTMAN, MARIO · 2013 to 2016
$1.2M
DELINEATING THE ROLE OF GENETIC INFLUENCES ON CANNABIS INVOLVEMENTK02DA032573 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2012 to 2021
$1.1M
NIAAA NIH HHS K05 AA017688NIAAA NIH HHS P50 AA011998NIAAA NIH HHS R01 AA017915NIAAA NIH HHS R01 AA021492NICHD NIH HHS R01 HD049024NIDA NIH HHS K02 DA032573NIDA NIH HHS R01 DA023368NIDA NIH HHS R01 DA023668
6 · The paper itself

Abstract

BACKGROUND AND

aimsSubstance use has been implicated in the onset and maintenance of risky sexual behaviors, which have particularly devastating consequences in young women. This study examined whether (i) adolescent onset of cannabis use is associated with repeated voluntary unprotected sex in women and (ii) whether this association persists after accounting for correlated familial influences.

designGeneral population sample of female twins.

settingMidwestern United States.

participantsA total of 2784 sexually active twin women (15.5% African American) aged 18-27 years (assessed 2002-05), including 119 dizygotic (DZ) and 115 monozygotic (MZ) discordant pairs. MEASUREMENTS: Self-report interview data on cannabis use that first occurred prior to age 17 (27.1%) and repeated voluntary unprotected sex (27.2%). Key covariates included early onset of regular drinking, regular smoking, sexual debut and menstruation as well as conduct disorder symptoms and childhood sexual abuse.

findingsCompared with never users and those who started using cannabis at a later age, adolescent cannabis users were more likely to report repeated voluntary unprotected sex [odds ratio (OR) = 2.69; 95% confidence interval (CI) = 2.24-3.22]. Genetic (r

conclusionsWomen who start using cannabis during adolescence appear to be more likely to report voluntary engagement in repeated unprotected sex than women who never use cannabis or who initiate cannabis use after adolescence. The results appear to be independent of shared genetic influences.

Indexed as

AdolescentAdultAdult Survivors of Child AbuseAge of OnsetCoitusFemaleHumansMarijuana UseMissouriTwins, DizygoticTwins, MonozygoticUnsafe SexYoung AdultCannabisdiscordantriskysexualtwinunprotected

Identifiers

PMID27317963
PMCPMC5056799

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.