ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2016
Acute kidney injury following hepatectomy for hepatocellular carcinoma: incidence, risk factors and prognostic value.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05361252 (Restrictive Versus Liberal Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Restrictive Versus Liberal Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection: a Prospective Randomised Trial of Perioperative Quality of Care
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Incidence and risk factors of acute kidney injury after abdominal surgery: a systematic review and meta-analysis.Annals of medicine · 2025Pooled it
- Acute Kidney Injury in Adult Patients With Hepatocellular Carcinoma After TACE or Hepatectomy Treatment.Frontiers in oncology · 2022Pooled it
- Safety of laparoscopic hepatectomy in patients with hepatocellular carcinoma and portal hypertension: interim analysis of an open prospective study.Surgical endoscopy · 2019Trial
- Perioperative Myocardial Injury and Acute Kidney Injury in Patients Undergoing Hepatic Resection: Incidence, Risk Factors, and Effects on Outcomes.Journal of clinical medicine · 2025Article
- Prediction of acute kidney injury in the immediate postoperative period following liver resection: a retrospective cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2025Article
- A Predictive Model for Acute Kidney Injury Based on Leukocyte-Related Indicators in Hepatocellular Carcinoma Patients Admitted to the Intensive Care Unit.Mediators of inflammation · 2025Article
- Article
- Development of a risk prediction model for acute kidney injury in liver transplant recipients.Frontiers in surgery · 2025Article
- Combining occlusion of the right hepatic vein with the Pringle maneuver in laparoscopic anatomic right posterior liver resection.Surgical endoscopy · 2024Article
- Predictors for 30-day mortality in hepatocellular carcinoma patients undergoing liver resection.Narra J · 2024Article
- Machine learning in liver surgery: Benefits and pitfalls.World journal of clinical cases · 2024Article
- The relationship between trajectories of renal oxygen saturation and acute kidney injury: a prospective cohort study with a secondary analysis.Aging clinical and experimental research · 2024Article
- Article
- Role of proenkephalin in the diagnosis of severe and subclinical acute kidney injury during the perioperative period of liver transplantation.Practical laboratory medicine · 2022Article
- Predictors of mortality within the first year post-hepatectomy for hepatocellular carcinoma.Journal of the Egyptian National Cancer Institute · 2022Article
- Risk factors and prediction of acute kidney injury after liver transplantation: Logistic regression and artificial neural network approaches.World journal of hepatology · 2022Article
- Development and validation of a risk nomogram for postoperative acute kidney injury in older patients undergoing liver resection: a pilot study.BMC anesthesiology · 2022Observational
- Skin autofluorescence as a novel predictor of acute kidney injury after liver resection.World journal of surgical oncology · 2021Observational
- Acute kidney injury following hepatectomy and its impact on long-term survival for patients with hepatocellular carcinoma.BJS open · 2021Article
- Impact of low serum hemoglobin on development of contrast-induced nephropathy (CIN) in patients with hepatocellular carcinoma (HCC) following transarterial chemoembolisation (TACE).International urology and nephrology · 2021Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute kidney injury (AKI) following hepatectomy remains understudied in terms of diagnosis, severity, recovery and prognostic value. The aim of this study was to assess the risk factors and prognostic value of AKI on short- and long-term outcomes following hepatectomy for hepatocellular carcinoma (HCC).
methodThis is a retrospective analysis of a single-center cohort of 457 consecutive patients who underwent hepatectomy for HCC. The KDIGO criteria were used for AKI diagnosis. The incidence, risk factors, and prognostic value of AKI were investigated.
resultsAKI occurred in 67 patients (15%). The mortality and major morbidity rates were significantly higher in patients with AKI (37% and 69%) than in those without (6% and 22%; p < 0.001). Renal recovery was complete in 35 (52%), partial in 25 (37%), and absent in 7 (11%) patients. Advanced age, an increased MELD score, major hepatectomy and prolonged duration of operation were identified as independent predictors of AKI. AKI was identified as the strongest independent predictor of postoperative mortality but did not impact survival.
conclusionAKI is a common complication after hepatectomy for HCC. Although its development is associated with poor short-term outcomes, it does not appear to be predictive of impaired long-term survival.
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