ArticleBritish journal of anaesthesia2016
Introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety in children.
Article in British journal of anaesthesia, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Comics on Anaesthesia's Anxiety in Paediatrics: A Randomized Controlled Trial
Developing and Testing the Effectiveness of Intelligent Customer-driven Solution for Pediatric Surgery Care on the Improvement of Outcomes of Parents and Their Children Undergoing Circumcision
Efficacy of an Educational Pop-Up Book in Preparing Children for Anesthesia: A Randomized Controlled Trial
Impact of the Information Leaflet on the Preoperative Anesthesia Knowledge and Anxiety Levels of Children and Parents Before the Pediatric Endoscopic Procedures
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- [Practice guideline for standardized construction of ambulatory surgery in pediatric otorhinolaryngology and head and neck surgery].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Guideline
- Effect of Educational Brochures on Preprocedural Anxiety in Pediatric Endoscopy: A Randomized Controlled Trial.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Trial
- Impact of a novel bundled information, education, & communication video on preoperative anxiety in paediatric patients: A randomised controlled trial.The Indian journal of medical research · 2025Trial
- Effect of interactive, multimedia-based home-initiated education on preoperative anxiety inchildren and their parents: a single-center randomized controlled trial.BMC anesthesiology · 2023Trial
- Effects of advance exposure to an animated surgery-related picture book on preoperative anxiety and anesthesia induction in preschool children: a randomized controlled trial.BMC pediatrics · 2022Trial
- Relaxation-guided imagery reduces perioperative anxiety and pain in children: a randomized study.European journal of pediatrics · 2019Trial
- Motivating Mothers to Recommend Their 20-Year-Old Daughters Receive Cervical Cancer Screening: A Randomized Study.Journal of epidemiology · 2018Trial
- Remimazolam: a comprehensive review.Anaesthesiology intensive therapy · 2025Review
- Remimazolam as a Novel Anesthetic in Pediatric Procedural Sedation and Anesthesia: A Narrative Review.Cureus · 2025Review
- A Scoping Review of Graphic Medicine Interventions to Promote Changes in Health Behavior, Health Service Engagement, and Health Outcomes.International journal of environmental research and public health · 2025Article
- Evaluating the efficacy of a smartphone application in reducing preoperative anxiety in children: A randomised controlled trial.Indian journal of anaesthesia · 2025Article
- Article
- Perioperative period from a pediatric perspective: a mixed-methods study.Frontiers in pediatrics · 2025Article
- Measuring Children's Stress via Saliva in Surgical and Endoscopic Procedures and Its Measurement Intention in the Community: Reality-Future Prospects.Children (Basel, Switzerland) · 2023Article
- Perception on Anxiety among Adolescents and Mental Health Professionals and Development of Comic Strip.Indian journal of psychological medicine · 2023Article
- EDFrontiers in medicine · 2023Article
- Research Progress on Risk Factors of Preoperative Anxiety in Children: A Scoping Review.International journal of environmental research and public health · 2022Article
- Parental presence and intranasal dexmedetomidine for the prevention of anxiety during anesthesia induction in children undergoing tonsillectomy and/or adenoidectomy surgery: A randomized controlled trial.Frontiers in pharmacology · 2022Article
- Effect of video games on preoperative anxiety in 3- to-6-year-old of a sample of Iranian children undergoing elective surgery.Journal of education and health promotion · 2022Article
- Emotional experiences of reading health educational manga encouraging behavioral changes: a non-randomized controlled trial.Health psychology and behavioral medicine · 2021Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the study was to determine whether the introduction of a paediatric anaesthesia comic information leaflet reduced preoperative anxiety levels of children undergoing major surgery. Secondary objectives were to determine whether the level of understanding of participants and other risk factors influence STAIC-S (State-Trait Anxiety Inventory for Children-State subscale) score in children.
methodsWe performed a randomized controlled parallel-group trial comparing preoperative anxiety between two groups of children aged >6 and <17 yr. Before surgery, the intervention group received a comic information leaflet at home in addition to routine information given by the anaesthetist at least 1 day before surgery. The control group received the routine information only. The outcome measure was the difference between STAIC-S scores measured before any intervention and after the anaesthetist's visit. A multiple regression analysis was performed to explore the influence of the level of education, the anxiety of parents, and the childrens' intelligence quotient on STAIC-S scores.
resultsOne hundred and fifteen children were randomized between April 2009 and April 2013. An intention-to-treat analysis on data from 111 patients showed a significant reduction (P=0.002) in STAIC-S in the intervention group (n=54, mean=-2.2) compared with the control group (n=57, mean=0.90). The multiple regression analysis did not show any influence on STAIC-S scores of the level of education, parental anxiety, or the intelligence quotient of the children.
conclusionsA paediatric anaesthesia comic information leaflet was a cheap and effective means of reducing preoperative anxiety, measured by STAIC-S, in children. CLINICAL TRIALS REGISTRATION: NCT 00841022.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.