Evidence map›Paper›PMID 27317043›Full record

ArticleDrug and alcohol dependence2016

Repeated measures latent class analysis of daily smoking in three smoking cessation studies.

Danielle E McCarthy, Lemma Ebssa, Katie Witkiewitz, Saul Shiffman

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Danielle E McCarthyRutgers, the State University of New Jersey, Department of Psychology and Institute for Health, Health Care Policy and Aging Research, 112 Paterson St., New Brunswick, NJ 08901, USA. Electronic address: demccart@rci.rutgers.edu.
Lemma EbssaRutgers, the State University of New Jersey, Department of Psychology and Institute for Health, Health Care Policy and Aging Research, 112 Paterson St., New Brunswick, NJ 08901, USA. Electronic address: lemma@rci.rutgers.edu.
Katie WitkiewitzDepartment of Psychology and Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Blvd SE, MSC 11-6280, Albuquerque, NM 87106, USA. Electronic address: katiew@unm.edu.
Saul ShiffmanUniversity of Pittsburgh, Department of Psychology, Bellefield Professional Building, 130N. Bellefield Ave., Pittsburgh, PA 15260-2695, USA. Electronic address: shiffman@pinneyassociates.com.

Funding

RELAPSE: LINKING SCIENCE AND PRACTICEP50CA084724 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI FIORE, MICHAEL C · 1999 to 2003
$8.9M
Tobacco Dependence: Treatment and OutcomesP50DA019706 · NIDA · UNIVERSITY OF WISCONSIN-MADISON · PI JACKSON, THOMAS C · 2004 to 2008
$8.6M
Accelerating Smoking Relapse Research Using Longitudinal Models of EMA DataR01DA033303 · NIDA · RUTGERS, THE STATE UNIV OF N.J. · PI MCCARTHY, DANIELLE ERIN, SHIFFMAN, SAUL · 2012 to 2014
$676k
NCI NIH HHS P50 CA084724NIDA NIH HHS P50 DA019706NIDA NIH HHS R01 DA033303
6 · The paper itself

Abstract

backgroundPerson-centered approaches to the study of behavior change, such as repeated measures latent class analysis (RMLCA), can be used to identify patterns of change and link these to later behavior change outcomes.

methodsDaily smoking status data from three smoking cessation studies (N=287, N=334, and N=403) were submitted to RMLCA to identify latent classes of smokers based on patterns of abstinence across the first 27days of a quit attempt. Three-month biochemically verified abstinence rates were compared among latent classes with particular patterns of smoking across days. Pharmacotherapy variables and baseline individual differences were added as covariates of latent class membership.

resultsResults of separate and pooled analyses supported a five-class solution that replicated across studies. Latent classes included a large class that achieved immediate stable abstinence, a smaller class of cessation failures, and three classes with partial abstinence that increased, decreased, or remained stable over time. Three-month point-prevalence abstinence rates varied among the latent classes, with 38-55% abstinent among early quitters, 3-20% abstinent among those who smoked intermittently throughout the first 27days, and fewer than 5% abstinent in the classes marked by little or delayed change in smoking. High-dose nicotine patch and bupropion promoted membership in abstinent classes. Demographics, nicotine dependence, and craving were related to latent class in multiple studies and pooled analyses.

conclusionsWe identified five patterns of smoking behavior in the first weeks of a smoking cessation attempt. These patterns are robust across multiple studies and are related to later point-prevalence abstinence rates.

Indexed as

AdolescentAdultBupropionCravingFemaleHumansMaleMiddle AgedModels, StatisticalRandomized Controlled Trials as TopicSmokingSmoking CessationTobacco Use Cessation DevicesTobacco Use DisorderYoung AdultBupropionCessationRepeated measures latent class analysisSmokingTobacco

Identifiers

PMID27317043
PMCPMC4946336

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.