ArticleNeurotoxicity research2016
Frequency of Spontaneous BOLD Signal Differences between Moderate and Late Preterm Newborns and Term Newborns.
Article in Neurotoxicity research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- Regional BOLD variability reflects microstructural maturation and neuronal ensheathment in the preterm infant cortex.Nature communications · 2026Article
- Aperiodic parameters of the fMRI power spectrum associate with preterm birth and neonatal age.Communications biology · 2026Article
- Dysfunctional brain connectivity and cognition in late preterm infants: novel perspectives on neurodevelopment and learning.Frontiers in synaptic neuroscience · 2026Review
- Neurochemical-hemodynamic-electrophysiological coupling in the neonatal brain: a multimodal MRS-fMRI-EEG investigation.Frontiers in neuroscience · 2026Article
- Cerebral Ultrasound at Term-Equivalent Age: Correlations with Neuro-Motor Outcomes at 12-24 Months Corrected Age.Children (Basel, Switzerland) · 2024Article
- Differences in the amplitude of low-frequency fluctuations of spontaneous brain activity between preterm and term infants.Frontiers in neurology · 2024Article
- Exploring functional brain activity in neonates: A resting-state fMRI study.Developmental cognitive neuroscience · 2020Article
- A machine learning investigation of volumetric and functional MRI abnormalities in adults born preterm.Human brain mapping · 2019Article
- Rapid Infant Prefrontal Cortex Development and Sensitivity to Early Environmental Experience.Developmental review : DR · 2018Article
- Commentary - The late preterm infant: Vulnerable cerebral cortex and large burden of disability.Journal of neonatal-perinatal medicineArticle
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Little is known about the frequency features of spontaneous neural activity in the brains of moderate and late preterm (MLPT) newborns. We used resting-state functional magnetic resonance imaging (rs-fMRI) and the amplitude of low-frequency fluctuation (ALFF) method to investigate the frequency properties of spontaneous blood oxygen level-dependent (BOLD) signals in 26 MLPT and 35 term newborns. Two frequency bands, slow-4 (0.027-0.073 Hz) and slow-5 (0.01-0.027 Hz), were analyzed. Our results showed widespread differences in ALFF between the two bands; differences occurred mainly in the primary sensory and motor cortices and to a lesser extent in association cortices and subcortical areas. Compared with term newborns, MLPT newborns showed significantly altered neural activity predominantly in the primary sensory and motor cortices and in the posterior cingulate gyrus/precuneus. In addition, a significant interaction between frequency bands and groups was observed in the primary somatosensory cortex. Intriguingly, these primary sensory and motor regions have been proven to be the major cortical hubs during the neonatal period. Our results revealed the frequency of spontaneous BOLD signal differences between MLPT and term newborns, which contribute to the understanding of regional development of spontaneous brain rhythms of MLPT newborns.
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