Evidence map›Paper›PMID 27315484›Full record

ArticleCell2016

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

Christopher J Tape, Stephanie Ling, Maria Dimitriadi, Kelly M McMahon, Jonathan D Worboys, Hui Sun Leong, Ida C Norrie, Crispin J Miller, George Poulogiannis, Douglas A Lauffenburger and 1 more

Abstract readPublished Erratum
In one paragraph

Article in Cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

  1. Article
  2. Pancreatic cancer-derived extracellular vesicles enhance chemoresistance by delivering KRASMolecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Spatial biology of cancer evolution.Nature reviews. Genetics · 2023
    Review
  8. Review
  9. Patterns of Ciliation and Ciliary Signaling in Cancer.Reviews of physiology, biochemistry and pharmacology · 2023
    Review
  10. Article
  11. The importance of being CAFs (in cancer resistance to targeted therapies).Journal of experimental & clinical cancer research : CR · 2022
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Highlights on the Role ofInternational journal of molecular sciences · 2021
    Review
  19. Article
  20. Pancreatic Adenocarcinoma Therapeutics Targeting RTK and TGF Beta Receptor.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Christopher J Tape
Stephanie Ling
Maria Dimitriadi
Kelly M McMahon
Jonathan D Worboys
Hui Sun Leong
Ida C Norrie
Crispin J Miller
George Poulogiannis
Douglas A Lauffenburger
Claus Jørgensen

Funding

Cancer Research UK 12905
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID27315484
PMCPMC5628167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.