Evidence map›Paper›PMID 27314857›Full record

SynthesisAnnals of the American Thoracic Society2016

Global Associations between Air Pollutants and Chronic Obstructive Pulmonary Disease Hospitalizations. A Systematic Review.

Elizabeth Moore, Lia Chatzidiakou, Moyosore-Oluwa Kuku, Roderic L Jones, Liam Smeeth, Sean Beevers, Frank J Kelly, Benjamin Barratt, Jennifer K Quint

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Annals of the American Thoracic Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 7 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 7 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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  5. Pooled it
  6. A Systematic Review and Meta-Analysis of Short-Term Ambient Ozone Exposure and COPD Hospitalizations.International journal of environmental research and public health · 2020
    Pooled it
  7. Pooled it
  8. Trial
  9. Health effects of air pollution on chronic respiratory diseases.The Korean journal of internal medicine · 2026
    Review
  10. Article
  11. Article
  12. Article
  13. Air Pollution and Effects of Tropospheric Ozone (OInternational journal of environmental research and public health · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Elizabeth Moore1 National Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0003-1660-7598
Lia Chatzidiakou2 Centre for Atmospheric Science, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.
Moyosore-Oluwa Kuku3 Division of Medicine, University College London, London, United Kingdom.
Roderic L Jones2 Centre for Atmospheric Science, Department of Chemistry, University of Cambridge, Cambridge, United Kingdom.
Liam Smeeth4 London School of Hygiene and Tropical Medicine, London, United Kingdom; and.
Sean Beevers5 Analytical & Environmental Sciences Division, King's College London, London, United Kingdom.
Frank J Kelly5 Analytical & Environmental Sciences Division, King's College London, London, United Kingdom.
Benjamin Barratt5 Analytical & Environmental Sciences Division, King's College London, London, United Kingdom.
Jennifer K Quint1 National Heart and Lung Institute, Imperial College London, London, United Kingdom.
King's College London · GBLung Institute · USUniversity of Cambridge · GBThe London College · GBUniversity of London · GB

Funding

Medical Research Council G0801056Medical Research Council MR/K006584/1Medical Research Council MR/L01341X/1Medical Research Council MR/L019744/1
6 · The paper itself

Abstract

rationaleExacerbations are key events in chronic obstructive pulmonary disease (COPD), affecting lung function decline and quality of life. The effect of exposure to different air pollutants on COPD exacerbations is not clear.

objectivesTo carry out a systematic review, examining associations between air pollutants and hospital admissions for COPD exacerbations.

methodsMEDLINE, Embase, BIOSIS, Science Citation Index, and the Air Pollution Epidemiology Database were searched for publications published between 1980 and September 2015. Inclusion criteria were focused on studies presenting solely a COPD outcome defined by hospital admissions and a measure of gaseous air pollutants and particle fractions. The association between each pollutant and COPD admissions was investigated in metaanalyses using random effects models. Analyses were stratified by geographical clusters for investigation of the consistency of the evidence worldwide. MEASUREMENTS AND MAIN

resultsForty-six studies were included, and results for all the pollutants under investigation showed marginal positive associations; however, the number of included studies was small, the studies had high heterogeneity, and there was evidence of small-study bias. Geographical clustering of the effects of pollution on COPD hospital admissions was evident and reduced heterogeneity significantly.

conclusionsThe most consistent association was between a 1-mg/m

Indexed as

Quality of LifeAir PollutantsDisease ProgressionEnvironmental MonitoringGasesHumansParticulate MatterPatient AdmissionPulmonary Disease, Chronic ObstructiveAir PollutantsGasesParticulate Matterenvironmental monitoringgasesparticulate matterpatient admission

Identifiers

PMID27314857
PMCPMC5122486
OpenAlexW2421793033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.