ReviewJournal of Parkinson's disease2016
Ventilatory Dysfunction in Parkinson's Disease.
Review in Journal of Parkinson's disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04834258 (What Happens to Pulmonary Function and Functional Exercise Capacity When Walking Training is Combined With Respiratory Muscle Training in Patients With Parkinson's Disease), which is not on this map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
What Happens to Pulmonary Function and Functional Exercise Capacity When Walking Training is Combined With Respiratory Muscle Training in Patients With Parkinson's Disease: A Randomized Double-blind Controlled Trial
Who cites it
29 citing papers in PubMed, 70 citations in OpenAlex.
- Efficacy of Clotiazepam for Respiratory Dyskinesia in a Patient With Parkinsonism: A Case Report.Cureus · 2026Article
- Exercise-Induced Oxygen Desaturation and Cognitive Performance in Patients with Parkinson's Disease: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Dynamic Respiration-Neural Coupling in Substantia Nigra across Sleep and Anesthesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Advice to people with Parkinson's in my clinic: Get a cardiopulmonary exercise test.Journal of Parkinson's disease · 2025Article
- Can walking capacity predict respiratory functions of people with Parkinson's disease?Frontiers in neurology · 2025Article
- Respiratory Dysfunction and Abnormal Hypoxic Ventilatory Response in Mild to Moderate Parkinson's Disease.Movement disorders clinical practice · 2024Article
- Impact of Serotonergic 5HTInternational journal of molecular sciences · 2024Article
- Identifying Subtle Motor Deficits Before Parkinson's Disease is Diagnosed: What to Look for?Journal of Parkinson's disease · 2024Review
- Pulmonary function and medication effect in mild-stage subjects with Parkinson's disease.Arquivos de neuro-psiquiatria · 2022Article
- Artificial intelligence-enabled detection and assessment of Parkinson's disease using nocturnal breathing signals.Nature medicine · 2022Article
- Prosodic characteristics of prepausal words produced by patients with neurodegenerative disease.Speech prosody (Urbana, Ill.) · 2022Article
- Respiratory Abnormalities in Parkinson's Disease: What Do We Know from Studies in Humans and Animal Models?International journal of molecular sciences · 2022Review
- Experienced Respiratory Symptoms and the Impact on Daily Life from the Perspective of People with Parkinson's Disease: A Grounded Theory.Journal of Parkinson's disease · 2022Article
- Effects of an Aquatic Physical Exercise Program on Ventilatory Parameters in People with Parkinson's Disease.Parkinson's disease · 2022Article
- Exercise Intolerance and Oxygen Desaturation in Patients with Parkinson's Disease: Triggers for Respiratory Rehabilitation?International journal of environmental research and public health · 2021Article
- NaJournal of neural transmission (Vienna, Austria : 1996) · 2021Review
- Unraveling the Mechanisms Underlying Irregularities in Inspiratory Rhythm Generation in a Mouse Model of Parkinson's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Article
- Gut Microbiome Changes with Osteopathic Treatment of Constipation in Parkinson's Disease: A Pilot Study.Neurology (E-Cronicon) · 2021Article
- Systemic oxidative stress and cognitive function in Parkinson's disease with different PWMH or DWMH lesions.BMC neurology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to some other neurodegenerative diseases, little is known about ventilatory dysfunction in Parkinson's disease (PD). To assess the spectrum of ventilation disorders in PD, we searched for and reviewed studies of dyspnea, lung volumes, respiratory muscle function, sleep breathing disorders and the response to hypoxemia in PD. Among the studies, we identified some limitations: (i) small study populations (mainly composed of patients with advanced PD), (ii) the absence of long-term follow-up and (iii) the absence of functional evaluations under "off-drug" conditions. Although there are many reports of abnormal spirometry data in PD (mainly related to impairment of the inspiratory muscles), little is known about hypoventilation in PD. We conclude that ventilatory dysfunction in PD has been poorly studied and little is known about its frequency and clinical relevance. Hence, there is a need to characterize the different phenotypes of ventilation disorders in PD, study their relationships with disease progression and assess their prognostic value.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.