Evidence map›Paper›PMID 27313997›Full record

ReviewFrontiers in bioengineering and biotechnology2016

Patterning Biomaterials for the Spatiotemporal Delivery of Bioactive Molecules.

Silvia Minardi, Francesca Taraballi, Laura Pandolfi, Ennio Tasciotti

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Engineering Spatiotemporal Control in Vascularized Tissues.Bioengineering (Basel, Switzerland) · 2022
    Review
  3. Article
  4. Article
  5. Nanostructured Biomaterials for Bone Regeneration.Frontiers in bioengineering and biotechnology · 2020
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Silvia MinardiDepartment of Regenerative Medicine, Houston Methodist Research Institute , Houston, TX , USA.
Francesca TaraballiDepartment of Regenerative Medicine, Houston Methodist Research Institute , Houston, TX , USA.
Laura PandolfiDepartment of Regenerative Medicine, Houston Methodist Research Institute, Houston, TX, USA; College of Materials Science and Engineering, University of Chinese Academy of Science, Beijing, China.
Ennio TasciottiDepartment of Regenerative Medicine, Houston Methodist Research Institute, Houston, TX, USA; Department of Orthopedics, Houston Methodist Hospital, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of tissue engineering is to promote the repair of functional tissues. For decades, the combined use of biomaterials, growth factors (GFs), and stem cells has been the base of several regeneration strategies. Among these, biomimicry emerged as a robust strategy to efficiently address this clinical challenge. Biomimetic materials, able to recapitulate the composition and architecture of the extracellular matrix, are the materials of choice, for their biocompatibility and higher rate of efficacy. In addition, it has become increasingly clear that restoring the complex biochemical environment of the target tissue is crucial for its regeneration. Toward this aim, the combination of scaffolds and GFs is required. The advent of nanotechnology significantly impacted the field of tissue engineering by providing new ways to reproduce the complex spatial and temporal biochemical patterns of tissues. This review will present the most recent approaches to finely control the spatiotemporal release of bioactive molecules for various tissue engineering applications.

Indexed as

biomaterialsdrug deliverygrowth factorspatterningtissue engineering

Identifiers

PMID27313997
PMCPMC4889608

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.