Evidence map›Paper›PMID 27313953›Full record

ReviewScientifica2016

Is Gastroparesis Found More Frequently in Patients with Cystic Fibrosis? A Systematic Review.

Juan E Corral, Corey W Dye, Maria R Mascarenhas, Jamie S Barkin, Matthias Salathe, Baharak Moshiree

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Scientifica, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04210427 (Cystic Fibrosis and Gut Dysmotility), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04210427 phase4completednot on this mapstarted 2019, after this paper: background citation

Cystic Fibrosis and Gut Dysmotility: The Effect of Polyethylene Glycol (PEG) on Intestinal Transit

TypeinterventionalSponsorSt. Louis UniversityRan2019 to 2023Enrolled3ConditionsCystic Fibrosis Gastrointestinal DiseaseArmsPolyethylene Glycol 3350, SmartPill Motility System & PillCam Patency Capsule
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Impaired distal colonic pH in adults with cystic fibrosis.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  7. Article
  8. Review
  9. Luminal Gastrointestinal Manifestations of Cystic Fibrosis.Current gastroenterology reports · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Juan E CorralDepartment of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Corey W DyeDepartment of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Maria R MascarenhasDivision of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Jamie S BarkinDivision of Gastroenterology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Matthias SalatheDivision of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Baharak MoshireeDivision of Gastroenterology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
University of Miami · USChildren's Hospital of Philadelphia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is associated with different gastrointestinal motility disturbances and syndromes. We aim to assess gastric emptying in patients with CF compared to healthy controls by a systematic review of existing literature. Medical databases and abstracts from major gastroenterology and CF meetings were reviewed. Emptying times in CF patients were compared with healthy controls using random effects models. Subgroup analysis stratified results by age and diagnostic modality. Nineteen studies from 7 countries included 574 subjects (359 CF patients and 215 controls). Using pooled analysis frequency of gastroparesis was high (38%, 95% CI 30-45%) but results were highly dependent on the diagnostic modality. Delayed gastric emptying is more common in CF compared to general population. Scintigraphy identified rapid gastric emptying in a subgroup of CF patients, but this finding disappeared with adequate pancreatic enzyme replacement and after other diagnostic modalities were included.

Identifiers

PMID27313953
PMCPMC4904114
OpenAlexW2408341312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.