Evidence map›Paper›PMID 27313844›Full record

ArticlePerioperative medicine (London, England)2016

Fluid resuscitation practice patterns in intensive care units of the USA: a cross-sectional survey of critical care physicians.

Timothy E Miller, Martin Bunke, Paul Nisbet, Charles S Brudney

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Perioperative medicine (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05938049 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Carotid Doppler and Inferior Vena Cava Measuerments for Volume Guided Management in Acute Kidney Injury Patients

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled60ConditionsAcute Kidney InjuryArmsIVC ultrasound & Carotid doppler
NCT06034990 recruitingnot on this mapstarted 2024, after this paper: background citation

ICU Fluid Utilization Survey in Southeast Asia

TypeobservationalSponsorChulalongkorn UniversityRan2024 to 2026Enrolled1,000ConditionsCritical IllnessArms10-min online survey
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Understanding the Harms of HES: A Review of the Evidence to Date.Turkish journal of anaesthesiology and reanimation · 2019
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Timothy E MillerDepartment of Anesthesiology, Duke University Medical Center, Durham, NC 27710 USA.
Martin BunkeDepartment of Medical Affairs, Grifols, 79 TW Alexander Dr. Bldg. 4101, Research Triangle Park, NC 27709 USA.
Paul NisbetOne Research, LLC, 1150 Hungry Neck Blvd., Suite C-303, Charleston, SC 29464 USA.
Charles S BrudneyDepartment of Anesthesiology, Duke University Medical Center, Durham, NC 27710 USA.
Duke Medical Center · USResearch Triangle Park Foundation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluid resuscitation is a cornerstone of intensive care treatment, yet there is a lack of agreement on how various types of fluids should be used in critically ill patients with different disease states. Therefore, our goal was to investigate the practice patterns of fluid utilization for resuscitation of adult patients in intensive care units (ICUs) within the USA.

methodsWe conducted a cross-sectional online survey of 502 physicians practicing in medical and surgical ICUs. Survey questions were designed to assess clinical decision-making processes for 3 types of patients who need volume expansion: (1) not bleeding and not septic, (2) bleeding but not septic, (3) requiring resuscitation for sepsis. First-choice fluid used in fluid boluses for these 3 patient types was requested from the respondents. Descriptive statistics were performed using a Kruskal-Wallis test to evaluate differences among the physician groups. Follow-up tests, including t tests, were conducted to evaluate differences between ICU types, hospital settings, and bolus volume.

resultsFluid resuscitation varied with respect to preferences for the factors to determine volume status and preferences for fluid types. The 3 most frequently preferred volume indicators were blood pressure, urine output, and central venous pressure. Regardless of the patient type, the most preferred fluid type was crystalloid, followed by 5 % albumin and then 6 % hydroxyethyl starches (HES) 450/0.70 and 6 % HES 600/0.75. Surprisingly, up to 10 % of physicians still chose HES as the first choice of fluid for resuscitation in sepsis. The clinical specialty and the practice setting of the treating physicians also influenced fluid choices.

conclusionsPractice patterns of fluid resuscitation varied in the USA, depending on patient characteristics, clinical specialties, and practice settings of the treating physicians.

Indexed as

AlbuminBleedingColloidsCrystalloidsFluid resuscitationIntensive care unitSepsisSurvey

Identifiers

PMID27313844
PMCPMC4910257
OpenAlexW2438918058

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.