Evidence map›Paper›PMID 27313005›Full record

ReviewCurrent genetics2017

How do cells know what shape they are?

Hui Kang, Daniel J Lew

Abstract readReview
In one paragraph

Review in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Hui KangDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.
Daniel J LewDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA. daniel.lew@duke.edu.ORCID http://orcid.org/0000-0001-7482-3585
Duke Medical Center · USDuke University · US

Funding

POLARITY ESTABLISHMENT IN YEASTR01GM062300 · NIGMS · DUKE UNIVERSITY · PI LEW, DANIEL J · 2001 to 2016
$5.0M
Spatiotemporal modeling of signal transduction in yeastR01GM079271 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELSTON, TIMOTHY C, ERREDE, BEVERLY · 2006 to 2017
$4.0M
Gradient Tracking and ChemotropismR01GM103870 · NIGMS · DUKE UNIVERSITY · PI ELSTON, TIMOTHY C, LEW, DANIEL J · 2013 to 2016
$1.8M
NIGMS NIH HHS R01 GM062300NIGMS NIH HHS R01 GM079271NIGMS NIH HHS R01 GM103870
6 · The paper itself

Abstract

Studies on a yeast cell cycle checkpoint that can delay mitosis depending on whether cells have built a bud have identified a "sensor" that seems to recognize the organization of filament-forming septin proteins. Innovative work applying correlative light and platinum replica electron microscopy suggests that the informative septin organization involves parallel alignment of septin filaments, and another striking study shows that septin filaments prefer to populate membranes that have positive micron-scale curvature. Together, these findings suggest a model for how cells may monitor aspects of their own shape to influence cell behavior.

Indexed as

Cell Cycle ProteinsCytoskeletal ProteinsStress, PhysiologicalYeastsCell Cycle ProteinsCytoskeletal ProteinsCell shapeCheckpointCurvatureElm1SeptinsSwe1

Identifiers

PMID27313005
PMCPMC5930002
OpenAlexW2431401827

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.