ArticleJournal of endocrinological investigation2016
Serum 25-hydroxyvitamin D status among Saudi children with and without a history of fracture.
Article in Journal of endocrinological investigation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Vitamin D level and fractures in children and adolescents: a systematic review and meta-analysis.Journal of bone and mineral metabolism · 2021Pooled it
- Association of serum 25(OH)Vit-D levels with risk of pediatric fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Pooled it
- Vitamin D-A Risk Factor for Bone Fractures in Children: A Population-Based Prospective Case-Control Randomized Cross-Sectional Study.International journal of environmental research and public health · 2023Trial
- Effect of Low-Dose Vitamin D Supplementation on Serum 25(OH)D in School Children and White-Collar Workers.Nutrients · 2017Trial
- Vitamin D status and adiposity in children with low-energy fractures: a prospective case-control study.European journal of pediatrics · 2026Observational
- Does Vitamin D Concentration Matter? The Consequential Effects of Serum Vitamin D Concentration and Supplementation on Paediatric Fracture Risk.Nutrients · 2026Article
- Low Vitamin D Levels Are Associated With Longer Healing Times in Pediatric Fracture Patients.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Comparison of 25-OH vitamin D levels between children with upper and those with lower extremity fractures: A prospective case-control study.Acta orthopaedica et traumatologica turcica · 2022Article
- Association of serum 25OHD levels with risk of paediatric fractures.Journal of bone and mineral metabolism · 2021Article
- High prevalence of vitamin D insufficiency in Chinese children with upper limb fractures.Genes & diseases · 2020Article
- Cardiometabolic healthy and unhealthy obesity: does vitamin D play a role?Endocrine connections · 2017Article
- Nutritional Rickets and Osteomalacia in the Twenty-first Century: Revised Concepts, Public Health, and Prevention Strategies.Current osteoporosis reports · 2017Review
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe significance of vitamin D deficiency in the incidence of bone fractures in children has been under investigated. Here, we aimed to associate serum 25-hydroxyvitamin D levels and fractures in Saudi children. MATERIALS AND
methodsThis cross-sectional study was conducted in 1022 Saudi children without fracture history [476 boys (age 14.56 ± 1.81, BMI 22.38 ± 5.81) and 546 girls (age 13.57 ± 1.67, BMI 22.24 ± 4.94)] and 234 Saudi children with a history of fracture [148 boys (age 14.25 ± 1.39, BMI 22.66 ± 6.08) and 86 girls (age 13.76 ± 1.35, BMI 21.33 ± 1.35)]. Anthropometric and fasting serum biochemical data were collected. Serum 25-hydroxyvitamin D level was assessed using electrochemiluminescence.
resultsMean circulating 25-hydroxyvitamin (25OH) D level in subjects with a history of fracture was significantly lower in both boys (p < 0.01) and girls (p < 0.01) than those without, however both groups had low mean 25(OH)D levels. Furthermore, age was positively associated with 25-hydroxyvitamin D in boys (p < 0.05) and negatively in girls (p < 0.05) with a history of fracture.
conclusionIn conclusion, vitamin D levels were significantly lower in children with a history of bone fractures in both boys and girls than those without such a history; even in the absence of fracture history, vitamin D status correction is warranted in the general Saudi pediatric population.
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