Evidence map›Paper›PMID 27312688›Full record

ArticleDiagnostic microbiology and infectious disease2016

Comparison of two chromogenic media for the detection of vancomycin-resistant enterococcal carriage by nursing home residents.

Theodore Gouliouris, Beth Blane, Hayley J Brodrick, Kathy E Raven, Kirsty E Ambridge, Angela D Kidney, Nazreen F Hadjirin, M Estée Török, Direk Limmathurotsakul, Sharon J Peacock

Open access · hybridAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Evaluation of a selective chromogenic medium for detecting vancomycin-resistant enterococci.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Theodore GouliourisDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom; Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, United Kingdom; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom. Electronic address: theo.gouliouris@doctors.org.uk.
Beth BlaneDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Hayley J BrodrickDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Kathy E RavenDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Kirsty E AmbridgeDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Angela D KidneyDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Nazreen F HadjirinDepartment of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
M Estée TörökDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom; Public Health England, Clinical Microbiology and Public Health Laboratory, Cambridge, United Kingdom; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Direk LimmathurotsakulMahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand.
Sharon J PeacockDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom; Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom; Mahidol-Oxford Tropical Medicine Research Unit, Mahidol University, Bangkok, Thailand; London School of Hygiene & Tropical Medicine, Keppel Street, London, United Kingdom.
University of Cambridge · GBMahidol Oxford Tropical Medicine Research Unit · TH

Funding

Medical Research Council MR/N029399/1Wellcome Trust 098600
6 · The paper itself

Abstract

We compared ChromID VRE and Brilliance VRE media for the detection of vancomycin-resistant enterococci (VRE). Using a panel of 28 enterococcal isolates, 10 vanA Enterococcus faecium and three vanA Enterococcus faecalis isolates grew as per manufacturers' instructions whilst growth of two vanC and eight vancomycin-susceptible enterococci was inhibited on both media. Important differences were noted in the selectivity and chromogenic properties of the two media for vanA Enterococcus raffinosus and vanB E. faecium. The two media were further evaluated using 295 stool samples from nursing home residents, 34 of which grew VRE (11.5%). ChromID and Brilliance had comparable sensitivity, which was increased markedly by prolonging incubation to 48 hours (from 29% to 82%, and from 41% to 85%, respectively) and by a pre-enrichment step (to 97% and 100%, respectively). Brilliance VRE agar had higher selectivity at 48 hours, and after pre-enrichment.

Indexed as

Nursing HomesBacteriological TechniquesCarrier StateChromogenic CompoundsCulture MediaEnterococcus faecalisEnterococcus faeciumFecesGram-Positive Bacterial InfectionsHumansProspective StudiesSensitivity and SpecificityVancomycin-Resistant EnterococciChromogenic CompoundsCulture MediaDetectionEnterococcus faeciumSelectivitySensitivityVancomycin-resistant enterococciVRE

Identifiers

PMID27312688
PMCPMC4950902
OpenAlexW2347196640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.