Evidence map›Paper›PMID 27312481›Full record

ArticleProceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine2016

Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene.

Raelene M Cowie, Silvia Carbone, Sean Aiken, John J Cooper, Louise M Jennings

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Third Body Wear of UHMWPE-on-PEEK-OPTIMA™.Materials (Basel, Switzerland) · 2020
    Article
  7. Article
  8. Influence of third-body particles originating from bone void fillers on the wear of ultra-high-molecular-weight polyethylene.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Raelene M CowieInstitute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK.
Silvia CarboneInstitute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK.
Sean AikenBiocomposites Ltd., Keele, UK.
John J CooperBiocomposites Ltd., Keele, UK.
Louise M JenningsInstitute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK l.m.jennings@leeds.ac.uk.
University of Leeds · GBNetComposites (United Kingdom) · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium sulfate bone void fillers are increasingly being used for dead space management in infected arthroplasty revision surgery. The presence of these materials as loose beads close to the bearing surfaces of joint replacements gives the potential for them to enter the joint becoming trapped between the articulating surfaces; the resulting damage to cobalt chrome counterfaces and the subsequent wear of ultra-high-molecular-weight polyethylene is unknown. In this study, third-body damage to cobalt chrome counterfaces was simulated using particles of the calcium sulfate bone void fillers Stimulan(®) (Biocomposites Ltd., Keele, UK) and Osteoset(®) (Wright Medical Technology, TN, USA) using a bespoke rig. Scratches on the cobalt chrome plates were quantified in terms of their density and mean lip height, and the damage caused by the bone void fillers was compared to that caused by particles of SmartSet GMV PMMA bone cement (DePuy Synthes, IN, USA). The surface damage from Stimulan(®) was below the resolution of the analysis technique used; SmartSet GMV caused 0.19 scratches/mm with a mean lip height of 0.03 µm; Osteoset(®) led to a significantly higher number (1.62 scratches/mm) of scratches with a higher mean lip height (0.04 µm). Wear tests of ultra-high-molecular-weight polyethylene were carried out in a six-station multi-axial pin on plate reciprocating rig against the damaged plates and compared to negative (highly polished) and positive control plates damaged with a diamond stylus (2 µm lip height). The wear of ultra-high-molecular-weight polyethylene was shown to be similar against the negative control plates and those damaged with third-body particles; there was a significantly higher (p < 0.001) rate of ultra-high-molecular-weight polyethylene wear against the positive control plates. This study showed that bone void fillers of similar composition can cause varying damage to cobalt chrome counterfaces. However, the lip heights of the scratches were not of sufficient magnitude to increase the wear of ultra-high-molecular-weight polyethylene above that of the negative controls.

Indexed as

Joint ProsthesisProsthesis FailureBiocompatible MaterialsBiomechanical PhenomenaBone CementsBone SubstitutesChromium AlloysHumansMaterials TestingPolyethylenesReoperationSurface PropertiesBiocompatible MaterialsBone CementsBone SubstitutesChromium AlloysPolyethylenesultra-high molecular weight polyethylenebone void fillercalcium sulfatein vitroKnee replacementthird-body damageultra-high-molecular-weight polyethylenewear

Identifiers

PMID27312481
PMCPMC4952026
OpenAlexW2434500742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.