Evidence map›Paper›PMID 27312475›Full record

Trial reportNeuroradiology2016

Occlusion assessment of intracranial aneurysms treated with the WEB device.

Jildaz Caroff, Cristian Mihalea, Titien Tuilier, Xavier Barreau, Christophe Cognard, Hubert Desal, Laurent Pierot, Armelle Arnoux, Jacques Moret, Laurent Spelle

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Neuroradiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. The RISE trial: A Randomized Trial on Intra-Saccular Endobridge devices.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Trial
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Persistent flow inside the Woven EndoBridge at angiographic follow-up: A multicenter study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  14. Article
  15. Article
  16. Geometry of intracranial aneurysms and of intrasaccular devices may influence aneurysmal occlusion rates after endovascular treatment.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  17. Article
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jildaz CaroffInterventional Neuroradiology NEURI Center, Hôpital Bicêtre, 78 rue du Général Leclerc, 94270, Le Kremlin Bicêtre, France. Jildaz.caroff@aphp.fr.ORCID http://orcid.org/0000-0002-0029-1835
Cristian MihaleaInterventional Neuroradiology NEURI Center, Hôpital Bicêtre, 78 rue du Général Leclerc, 94270, Le Kremlin Bicêtre, France.
Titien TuilierInterventional Neuroradiology, Hôpital Henri Mondor, Créteil, France.
Xavier BarreauInterventional Neuroradiology, CHU Hôpital Pellegrin, Bordeaux, France.
Christophe CognardInterventional Neuroradiology, CHU Hôpital Purpan, Toulouse, France.
Hubert DesalInterventional Neuroradiology, CHU Hôpital Nord Laennec, Nantes, France.
Laurent PierotInterventional Neuroradiology, Hôpital Maison-Blanche, Université Reims-Champagne-Ardenne, Reims, France.
Armelle ArnouxStatistics Department, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.
Jacques MoretInterventional Neuroradiology NEURI Center, Hôpital Bicêtre, 78 rue du Général Leclerc, 94270, Le Kremlin Bicêtre, France.
Laurent SpelleInterventional Neuroradiology NEURI Center, Hôpital Bicêtre, 78 rue du Général Leclerc, 94270, Le Kremlin Bicêtre, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Woven EndoBridge (WEB) system is an innovative device under evaluation for its capacity to treat wide-neck bifurcation intracranial aneurysms. The purpose of this study is to evaluate the use of the different occlusion scales available in clinical practice.

methodsSeven WEB-experienced neurointerventionalists were provided with 30 angiographic follow-up data sets and asked to grade each evaluation point according to the Bicêtre Occlusion Scale Score (BOSS), firstly based on DSA images only then using additional C-Arm VasoCT analysis. This BOSS evaluation was then converted into the WEB Occlusion Scale (WOS) and into a dichotomized scale (complete occlusion or not). To estimate the inter-rater agreement among the seven raters, an overall kappa coefficient [1] and its standard error (SE) were computed.

resultsUsing the five-grade BOSS, raters showed "moderate" agreement (kappa = 0.56). Using the three-grade WOS, agreement appeared slightly better (kappa = 0.59). Strongest inter-rater agreement was observed with a dichotomized version of the scale (complete occlusion or not), which enabled an "almost perfect" agreement (kappa = 0.88). VasoCT consistently enhanced the agreement particularly with regards depicting intra-WEB residual filling.

conclusionThe WOS is a consistent means to angiographically evaluate the WEB device efficiency. But the five-grade BOSS scale allows to identify aneurysm subgroups with differing risks of recurrence and/or rehemorrhage, which needs to be separated especially at the initial phase of evaluation of this innovative device. The additional use of VasoCT allows better inter-rater agreement in evaluating occlusion and specially in depicting intra-WEB persistent filling.

Indexed as

Blood Vessel ProsthesisStentsCerebral AngiographyComputed Tomography AngiographyEndovascular ProceduresEquipment Failure AnalysisHumansIntracranial AneurysmProsthesis DesignTreatment OutcomeEndovascular treatmentFlow disruptionIntracranial aneurysmsWEBWoven EndoBridge device

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.