ReviewNeurosurgical review2018
Unique features of pregnancy-related meningiomas: lessons learned from 148 reported cases and theoretical implications of a prolactin modulated pathogenesis.
Review in Neurosurgical review, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 45 citations in OpenAlex.
- A proteogenomic RNA processing mechanism drives sex differences in meningioma.Research square · 2026Article
- Dexamethasone Suppresses Already Low Estrogen Receptor Levels in Meningiomas.International journal of molecular sciences · 2026Review
- Human Meningiomas Reveal No Evidence of Neuroendocrine Differentiation.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026Article
- Brain Tumors in Pregnancy: A Review of Pathophysiology, Clinical Management, and Ethical Dilemmas.Cancers · 2025Review
- Depot Medroxyprogesterone Acetate and Risk of Meningioma in the US.JAMA neurology · 2025Article
- Oral contraceptives with progestogens desogestrel or levonorgestrel and risk of intracranial meningioma: national case-control study.BMJ (Clinical research ed.) · 2025Article
- The Molecular and Cellular Basis of Physiological Changes in Pregnancy and Its Implications in Neurologic and Ophthalmic Pathologies.International journal of molecular sciences · 2025Review
- Feasibility of simultaneous meningioma resection and cesarean section: A systematic review and a technical case presentation.World neurosurgery: X · 2025Article
- Intraoperative neuromonitoring of visual evoked potentials in a pregnant patient with meningioma: a case report.BMC neurology · 2024Article
- Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.Neuro-oncology · 2024Review
- Use of progestogens and the risk of intracranial meningioma: national case-control study.BMJ (Clinical research ed.) · 2024Article
- A Narrative Review on Neuro-Ophthalmological Manifestations That May Occur during Pregnancy.Life (Basel, Switzerland) · 2024Review
- Neurosurgical emergencies during pregnancy - Management dilemmas.Surgical neurology international · 2023Article
- Pregnancy and Childbirth in Women With Meningioma.Cureus · 2022Article
- Low-grade intracranial meningioma with bilateral pulmonary metastases incidentally detected postpartum: a case report and review of the literature.Journal of medical case reports · 2021Review
- Article
- The risk of developing a meningioma during and after pregnancy.Scientific reports · 2021Article
- Meningiomas of the Planum Sphenoidale and Tuberculum Sella.Journal of neurological surgery. Part B, Skull base · 2021Article
- Acute Subdural Hemorrhage of a Convexity Meningioma in the Postpartum Period; Case Report and Literature Review.Bulletin of emergency and trauma · 2019Article
- Management strategies and clinical follow-up of pregnant women with intracranial meningioma.Journal of medicine and lifeReview
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningiomas are some of the most frequently encountered adult intracranial tumors. Dramatic flare ups in size may occasionally be observed during pregnancy, leading to complicated clinical scenarios, with profound effects and substantial risks for both the mother's and the fetus's well-being. Despite the fact that such changes have largely been attributed to progesterone-based mechanisms, recent studies have put this theory into question or defied it. In order to assess these particular tumors carefully and to try and clarify the pathophysiology of such pregnancy-related meningioma growth, an in-depth review of the pertinent literature was undertaken. Based on clinical, radiographic, and pathological data gathered from 148 reported cases, we have found several unique features characterizing these pregnancy-related meningiomas. The presence of such observed features was found to be of high statistical significance when compared to their expected prevalence in the general population and included the following: (1) parasellar location, (2) anterior circulation blood supply, (3) visual symptoms at presentation, (4) high rate of clear-cell and chordoid morphology. A hypothesis is developed that these features are related to hormonal influences of the pituitary gland, and we discuss that this may be due to elevated prolactin levels. We encourage further research to test this exciting new theory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.