ArticleJournal of neural transmission (Vienna, Austria : 1996)2016
Heart rate variability in patients with post-traumatic stress disorder or borderline personality disorder: relationship to early life maltreatment.
Article in Journal of neural transmission (Vienna, Austria : 1996), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06821035 (Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences), which is not on this map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: Preventing Substance Use in Adversity- Impacted Youth
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autonomic dysfunction in posttraumatic stress disorder indexed by heart rate variability: a meta-analysis.Psychological medicine · 2020Pooled it
- Reduced vagal activity in borderline personality disorder is unaffected by intranasal oxytocin administration, but predicted by the interaction between childhood trauma and attachment insecurity.Journal of neural transmission (Vienna, Austria : 1996) · 2022Trial
- Teaching Youth & Families Self-Regulation Skills to Disrupt the Impact of Adverse Childhood Experiences: The THRIVE Study Protocol for a Randomized Controlled Trial.Research square · 2026Article
- Non-invasive physiological indicators of welfare in dairy cows.Animal welfare (South Mimms, England) · 2026Article
- Perceived sleep disturbance in healthy women with a history of childhood emotional abuse is not reflected in objective sleep measures or nocturnal heart rate variability.Frontiers in psychiatry · 2026Article
- The relationship of early life adversity and physiological synchrony within the therapeutic triad in horse-assisted therapy.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Long-term alteration of heart rate variability following childhood maltreatment: Results of a general population study.European psychiatry : the journal of the Association of European Psychiatrists · 2025Article
- Educational Level Modifies the Relationship between Standard Deviation of NN Intervals and Post-traumatic Stress Disorder Development over Two-years.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- The Relationship Between Impulse Control, Emotional and Cognitive Regulation Mechanisms and Heart Rate Variability.Turk psikiyatri dergisi = Turkish journal of psychiatry · 2025Article
- Metabolic Dysfunctions, Dysregulation of the Autonomic Nervous System, and Echocardiographic Parameters in Borderline Personality Disorder: A Narrative Review.International journal of molecular sciences · 2024Review
- Impact of surgery after injury on SDNN and posttraumatic stress disorder development over two years.Scientific reports · 2024Article
- Neuromodulation of Eating Disorders: A Review of Underlying Neural Network Activity and Neuromodulatory Treatments.Brain sciences · 2024Review
- Beyond clinical observations: a scoping review of AI-detectable observable cues in borderline personality disorder.Frontiers in psychiatry · 2024Article
- Civilian moral injury: associations with trauma type and high-frequency heart rate variability in two trauma-exposed community-based samples.Psychological medicine · 2023Article
- Experimental Induction of Emotional and Sexual Intimacy: Exploring the Validity of the German Fast Friends Procedure in Individuals with and without Childhood Maltreatment.Archives of sexual behavior · 2022Article
- Early life stress and autonomic response to acute mental stress in individuals with coronary heart disease.Journal of traumatic stress · 2022Article
- Nature-Based Relaxation Videos and Their Effect on Heart Rate Variability.Frontiers in psychology · 2022Article
- Severity of childhood maltreatment predicts reaction times and heart rate variability during an emotional working memory task in borderline personality disorder.European journal of psychotraumatology · 2022Article
- Emotion dysregulation and dissociation contribute to decreased heart rate variability to an acute psychosocial stressor in trauma-exposed Black women.Journal of psychiatric research · 2021Article
- Is Low Heart Rate Variability Associated with Emotional Dysregulation, Psychopathological Dimensions, and Prefrontal Dysfunctions? An Integrative View.Journal of personalized medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traumatic experiences have severe impact on the autonomous nervous system. Heart rate variability (HRV) is a reliable psychophysiological marker for the autonomous nervous system functioning. Reduced vagally mediated HRV has been found in patients with post-traumatic stress disorder (PTSD) and, in some studies, in patients with borderline personality disorder (BPD). In this study, we compared HRV parameters of patients with PTSD, current BPD, and BPD in remission with healthy volunteers in a 5 min resting-state electrocardiogram recording. 91 unmedicated female participants took part in the study (18 with PTSD, 27 with the current BPD, 23 with BPD in remission, and 23 healthy volunteers). We found significant group differences in both time-domain and frequency-domain (total power, low-frequency and high-frequency power) HRV parameters. Root mean square of the successive differences (RMSSD) was lowest in patients with PTSD (M = 48.6 ms, SD = 23.5 ms) followed by patients with BPD in remission (M = 57.7 ms, SD = 31.5 ms) and patients with the current BPD (M = 71.1 ms, SD = 44.5 ms), while the highest RMSSD was found in healthy volunteers (M = 84.1 ms, SD = 41.7 ms). Variance of HRV was higher in patients with BPD than in patients with PTSD. In addition, RMSSD was significantly negatively correlated with self-reported early life maltreatment assessed with the Childhood Trauma Questionnaire. Our findings point out a complex interaction between traumatic experiences, the functioning of the autonomic nervous system, and psychopathology. Alterations in HRV might be related to early life maltreatment or associated psychological factors rather than diagnostic entities.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.