ArticleClinical & experimental ophthalmology2016
Efficacy and cost-effectiveness of intracameral vancomycin in reducing postoperative endophthalmitis incidence in Australia.
Article in Clinical & experimental ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Comparative analysis of the safety and efficacy of intracameral cefuroxime, moxifloxacin and vancomycin at the end of cataract surgery: a meta-analysis.The British journal of ophthalmology · 2018Pooled it
- Trial
- Efficacy of prophylactic intracameral antibiotic in preventing endophthalmitis after cataract surgery.Arquivos brasileiros de oftalmologia · 2024Article
- Role of intracameral antibiotics in endophthalmitis prophylaxis following-cataract surgery.Indian journal of ophthalmology · 2020Article
- Utility of wound cultures in the management of open globe injuries: a 5-year retrospective review.Journal of ophthalmic inflammation and infection · 2020Article
- Intraoperative Cefuroxime Irrigation Prophylaxis for Acute-Onset Endophthalmitis After Phacoemulsification Surgery.Infection and drug resistance · 2020Article
- The Routine Use of Intracameral Antibiotics to Prevent Endophthalmitis After Cataract Surgery: How Good is the Evidence?Ophthalmology and therapy · 2018Review
- Antibiotic prophylaxis in cataract surgery - An evidence-based approach.Indian journal of ophthalmology · 2017Review
- Intracameral Antibiotics in the Shadow of Hemorrhagic Occlusive Retinal Vasculitis.Ophthalmology · 2017Article
- An updated estimate of costs of endophthalmitis following cataract surgery among Medicare patients: 2010-2014.Clinical ophthalmology (Auckland, N.Z.) · 2016Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndophthalmitis is a rare but devastating postoperative complication of cataract surgery. We aimed to describe the incidence of acute postoperative endophthalmitis in an Australian population over a 14-year period.
designThis was a retrospective longitudinal cohort study performed at Westmead Hospital, a major tertiary hospital in Sydney, Australia.
participantsPatients who had acute postoperative endophthalmitis within 6 weeks of their cataract surgery at Westmead Hospital were included.
methodsEndophthalmitis cases from 2000 to 2014 were identified from computerized diagnostic coding. These were cross-referenced with the cataract surgery list over this time period. The routine use of intracameral vancomycin at the end of cataract surgery was introduced in Westmead Hospital in 2004.
main outcome measuresWe quantified the incidence of acute postoperative endophthalmitis pre and post the routine use of intracameral vancomycin.
resultsA total of 14 805 cataract cases were performed at Westmead Hospital from 2000 to 2014. Seventeen cases of endophthalmitis were within 6 weeks post cataract surgery performed at Westmead Hospital. In the period 2000 to 2003, the incidence of postoperative endophthalmitis was 0.43% (11/2539). From 2004 to 2014, there was a dramatic decrease in the incidence of postoperative endophthalmitis to 0.049% (6/12 266, P < 0.0001).
conclusionsThere has been a nine-fold reduction in the rate of acute postoperative endophthalmitis with the use of intracameral vancomycin in cataract surgery. Post-cataract surgery endophthalmitis is now a relatively rare cause of endophthalmitis in this Australian population. Our study supports the routine use of intracameral vancomycin as postoperative endophthalmitis prophylaxis.
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