Evidence map›Paper›PMID 27311453›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2017

Computer derived transient ischemic dilation ratio for identifying extensive coronary artery disease using a CZT camera and imaging in the upright position.

Zenith A Jameria, Mouhamad Abdallah, Alok Dwivedi, Erica Washburn, Naseer Khan, Mahyar Khaleghi, Nischelle Kalakota, Myron C Gerson

Abstract read
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In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Transient ischemic dilation withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2026
    Trial
  2. Assessment of Myocardial CZT SPECT Recording in a Forward-Leaning Bikerlike Position.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Trial
  3. Article
  4. Article
  5. Prognostic value of absent left ventricular ejection fraction reserve with regadenoson SPECT MPI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. Review of cardiovascular imaging in the Journal of Nuclear Cardiology in 2017. Part 2 of 2: Myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Review
  7. Transient ischemic dilation: An old but not obsolete marker of extensive coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  8. Normal limits for transient ischemic dilation withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Zenith A JameriaDivision of Cardiology, Department of Internal Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Mouhamad AbdallahDivision of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH, 45267-0542, USA.
Alok DwivediDivision of Biostatistics and Epidemiology, Department of Biomedical Sciences, Texas Tech University Health Science Center, El Paso, TX, USA.
Erica WashburnDivision of Nuclear Medicine, Department of Radiology, University of Cincinnati Medical Center, Cincinnati, OH, USA.
Naseer KhanDivision of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH, 45267-0542, USA.
Mahyar KhaleghiDivision of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH, 45267-0542, USA.
Nischelle KalakotaUniversity of Cincinnati College of Medicine, University of Cincinnati, Cincinnati, OH, USA.
Myron C GersonDivision of Cardiology, Department of Internal Medicine, University of Cincinnati Medical Center, 231 Albert Sabin Way, Cincinnati, OH, 45267-0542, USA. myron.gerson@uc.edu.
University of Cincinnati Medical Center · USSabin Vaccine Institute · USTexas Tech University · USUniversity of Cincinnati · USUniversity of Illinois Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransient ischemic dilation (TID) of the left ventricle (LV) has not been validated as a marker of extensive coronary artery disease (CAD) for studies using a cadmium-zinc-telluride (CZT) camera with upright imaging.

methodsTID ratios were obtained from upright stress and rest images on a CZT camera. Separate cut-off values were determined for exercise and for regadenoson stress. The cutoffs were then applied to 28 patients with extensive CAD and 101 patients without extensive CAD.

resultsWith treadmill exercise, an upright TID ratio ≥1.16 provided a positive predictive value of 50% and a negative predictive value of 85.4% for the identification of extensive CAD. In the regadenoson group, an upright TID ratio of 1.29 provided a positive predictive value of 20% and a negative predictive value of 75.9%. Although not an independent predictor of extensive CAD in all subjects, in subjects with a normal upright LVEF, it provided a predictive value by receiver operating characteristics comparable to the SSS.

conclusionsIncreased upright TID measurements on a CZT camera are associated with extensive CAD. The upright TID measurements can serve in an adjunctive role to SSS, and may be most effective in patients with a normal upright exercise LVEF.

Indexed as

Image Processing, Computer-AssistedMyocardial Perfusion ImagingTomography, Emission-Computed, Single-PhotonAgedCadmiumCohort StudiesCoronary AngiographyCoronary Artery DiseaseDiagnosis, Computer-AssistedDilatationExercise TestFemaleHeart VentriclesHumansIschemiaMaleCadmiumCdZnTePurinesPyrazolesregadenosonTelluriumZincCadmium-zinc-telluridecoronary artery diseaseischemic dilation (TID)myocardial perfusion imaging: SPECTtransient

Identifiers

PMID27311453
OpenAlexW2438451818

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.