ReviewJournal of applied physiology (Bethesda, Md. : 1985)2016
Cardiovascular control during whole body exercise.
Review in Journal of applied physiology (Bethesda, Md. : 1985), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Deconstructing the Ergogenic Effects of Photobiomodulation: A Systematic Review and Meta-analysis of its Efficacy in Improving Mode-Specific Exercise Performance in Humans.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Early Endothelial Dysfunction in Type 1 Diabetes Is Accompanied by an Impairment of Vascular Smooth Muscle Function: A Meta-Analysis.Frontiers in endocrinology · 2020Pooled it
- Exercise and Autonomic Cardiovascular Function-Insights From Spinal Cord-Injured Humans: A Narrative Review.Acta physiologica (Oxford, England) · 2026Review
- The efficacy and physiological bases of small muscle mass exercise in health and disease.Experimental physiology · 2026Review
- Impact of physical activity on ethoxy- and propoxypropanol human toxicokinetics in vivo.Archives of toxicology · 2025Article
- Impaired oxygen consumption kinetics and autonomic dysfunction contribute to increased fatigue in obese young males during sustained exercise.Journal of exercise rehabilitation · 2025Article
- Diabetic kidney disease and cardiac autonomic neuropathy: insights on exercise rehabilitation.Journal of nephrology · 2025Review
- A Comparative Analysis of Acute Physiological and Perceptual Responses in Whole-Body and Ergometer-Based High-Intensity Interval Training Protocols.Sports (Basel, Switzerland) · 2024Article
- A century of exercise physiology: key concepts in neural control of the circulation.European journal of applied physiology · 2024Review
- Home-Based Exercise Training and Cardiac Autonomic Neuropathy in Kidney Transplant Recipients with Type-II Diabetes Mellitus.Life (Basel, Switzerland) · 2023Article
- Pathophysiological Mechanisms by which Heat Stress Potentially Induces Kidney Inflammation and Chronic Kidney Disease in Sugarcane Workers.Nutrients · 2020Article
- Exercise and Cardiovascular Risk among Masters Athletes with Type 2 Diabetes.Current diabetes reports · 2019Review
- Flow does not alter eNOS phosphoryation at Ser1179 or Thr495 in preconstricted mouse mesenteric arteries.Physiological reports · 2018Article
- Exercising in Air Pollution: The Cleanest versus Dirtiest Cities Challenge.International journal of environmental research and public health · 2018Article
- Cardiovascular Benefits of Moderate Exercise Training in Marfan Syndrome: Insights From an Animal Model.Journal of the American Heart Association · 2017Article
- Data inconsistencies and inaccuracies combined with methodological problems render physiological interpretation suspect.European journal of applied physiology · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been considered whether during whole body exercise the increase in cardiac output is large enough to support skeletal muscle blood flow. This review addresses four lines of evidence for a flow limitation to skeletal muscles during whole body exercise. First, even though during exercise the blood flow achieved by the arms is lower than that achieved by the legs (∼160 vs. ∼385 ml·min(-1)·100 g(-1)), the muscle mass that can be perfused with such flow is limited by the capacity to increase cardiac output (42 l/min, highest recorded value). Secondly, activation of the exercise pressor reflex during fatiguing work with one muscle group limits flow to other muscle groups. Another line of evidence comes from evaluation of regional blood flow during exercise where there is a discrepancy between flow to a muscle group when it is working exclusively and when it works together with other muscles. Finally, regulation of peripheral resistance by sympathetic vasoconstriction in active muscles by the arterial baroreflex is critical for blood pressure regulation during exercise. Together, these findings indicate that during whole body exercise muscle blood flow is subordinate to the control of blood pressure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.