Evidence map›Paper›PMID 27310834›Full record

ArticleDrug and chemical toxicology2017

Effects of titanium dioxide nanoparticles on human keratinocytes.

Clayton Wright, Anand Krishnan V Iyer, Liying Wang, Nianqiang Wu, Juan S Yakisich, Yon Rojanasakul, Neelam Azad

Open access · greenAbstract read
In one paragraph

Article in Drug and chemical toxicology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. The potential adverse human health effects of metal-containing nanoparticles: a scoping review.Journal of occupational medicine and toxicology (London, England) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. The Potential Key Role of the NRF2/NQO1 Pathway in the Health Effects of Arsenic Pollution on SCC.International journal of environmental research and public health · 2022
    Article
  10. Review
  11. Review
  12. Review
  13. Exposure Route of TiONanomaterials (Basel, Switzerland) · 2020
    Review
  14. Interactions of TiOChemical research in toxicology · 2020
    Article
  15. Amelioration of titanium dioxide nanoparticle reprotoxicity by the antioxidants morin and rutin.Environmental science and pollution research international · 2019
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Clayton Wrighta Department of Pharmaceutical Sciences , Hampton University , Hampton , VA , USA.
Anand Krishnan V Iyera Department of Pharmaceutical Sciences , Hampton University , Hampton , VA , USA.
Liying Wangb Allergy and Clinical Immunology Branch, National Institute for Occupational Safety and Health , Morgantown , WV , USA.
Nianqiang Wuc Department of Mechanical & Aerospace Engineering , and.
Juan S Yakisicha Department of Pharmaceutical Sciences , Hampton University , Hampton , VA , USA.
Yon Rojanasakuld Department of Pharmaceutical and Pharmacological Sciences , West Virginia University , Morgantown , WV , USA.
Neelam Azada Department of Pharmaceutical Sciences , Hampton University , Hampton , VA , USA.
Hampton University · USNational Institute for Occupational Safety and Health · USWest Virginia University · US

Funding

Anti-Tumorigenic Potential of Novel Digitoxin AnaloguesSC1CA173069 · NCI · HAMPTON UNIVERSITY · PI IYER, ANAND K. · 2012 to 2016
$1.3M
Impact of Oxidative Stress-Regulated Angiogenesis in Pulmonary FibrosisSC1HL112630 · NHLBI · HAMPTON UNIVERSITY · PI AZAD, NEELAM · 2011 to 2015
$1.3M
Targeting Lipogenic and Angiogenic Mediators in Pulmonary FibrosisSC1GM121287 · NIGMS · HAMPTON UNIVERSITY · PI AZAD, NEELAM · 2018 to 2021
$1.3M
Intramural CDC HHS CC999999NCI NIH HHS SC1 CA173069NHLBI NIH HHS SC1 HL112630NIGMS NIH HHS SC1 GM121287
6 · The paper itself

Abstract

Titanium dioxide (TiO

Indexed as

ApoptosisApoptosis Regulatory ProteinsBlotting, WesternCaspasesCell Culture TechniquesCell LineCell SurvivalCollagenEnzyme-Linked Immunosorbent AssayHumansKeratinocytesNanoparticlesOxidative StressParticle SizeReactive Oxygen SpeciesSkinApoptosis Regulatory ProteinsCaspasesCollagenReactive Oxygen SpeciesTitaniumtitanium dioxideapoptosiskeratinocytesnanoparticlesreactive oxygen speciesTitanium dioxide

Identifiers

PMID27310834
PMCPMC5161738
OpenAlexW2431214539

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.