Evidence map›Paper›PMID 27310353›Full record

ArticleAmerican journal of public health2016

Ethical and Psychosocial Considerations in Informing HIV-Exposed Uninfected Children That They Were Exposed to HIV and Antiretroviral Medications In Utero.

Robert Klitzman, Claude A Mellins, Morgan M Philbin, Elaine J Abrams, Robert H Remien

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. DisclosingJournal of the International AIDS Society · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robert KlitzmanRobert Klitzman is with the Masters of Bioethics Program, Columbia University, New York, NY. Claude A. Mellins, Morgan M. Philbin, and Robert H. Remien are with the HIV Center for Clinical and Behavioral Studies and Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY. Elaine J. Abrams is with the Mailman School of Public Health, International Center for AIDS Care and Treatment Programs, Columbia University.
Claude A MellinsRobert Klitzman is with the Masters of Bioethics Program, Columbia University, New York, NY. Claude A. Mellins, Morgan M. Philbin, and Robert H. Remien are with the HIV Center for Clinical and Behavioral Studies and Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY. Elaine J. Abrams is with the Mailman School of Public Health, International Center for AIDS Care and Treatment Programs, Columbia University.
Morgan M PhilbinRobert Klitzman is with the Masters of Bioethics Program, Columbia University, New York, NY. Claude A. Mellins, Morgan M. Philbin, and Robert H. Remien are with the HIV Center for Clinical and Behavioral Studies and Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY. Elaine J. Abrams is with the Mailman School of Public Health, International Center for AIDS Care and Treatment Programs, Columbia University.
Elaine J AbramsRobert Klitzman is with the Masters of Bioethics Program, Columbia University, New York, NY. Claude A. Mellins, Morgan M. Philbin, and Robert H. Remien are with the HIV Center for Clinical and Behavioral Studies and Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY. Elaine J. Abrams is with the Mailman School of Public Health, International Center for AIDS Care and Treatment Programs, Columbia University.
Robert H RemienRobert Klitzman is with the Masters of Bioethics Program, Columbia University, New York, NY. Claude A. Mellins, Morgan M. Philbin, and Robert H. Remien are with the HIV Center for Clinical and Behavioral Studies and Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York, NY. Elaine J. Abrams is with the Mailman School of Public Health, International Center for AIDS Care and Treatment Programs, Columbia University.
New York Psychoanalytic Society and Institute · US

Funding

The Statistics, Data Science, and Data Management (SDM) CoreP30MH043520 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI Claude Ann Mellins · 2003 to 2026
$48.2M
INSPIRE : Interdisciplinary Social and Behavioral Science Prevention and Intervention REsearch in HIVT32MH019139 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Claude Ann Mellins, Jae M. Sevelius · 1989 to 2026
$10.8M
NIMHD NIH HHS L60 MD009069NIMH NIH HHS P30 MH043520NIMH NIH HHS T32 MH019139
6 · The paper itself

Abstract

We build on what is known about the potential long-term health effects of perinatal antiretroviral medication exposure to examine ethical and psychosocial issues associated with disclosure by applying lessons from other health conditions, theories of child and adolescent development and rights, and the relevant literature and legal contexts. We present 2 cases to highlight potential issues; apply a bioethical framework that includes principles of autonomy, beneficence, nonmaleficence, and justice; and explore other factors, including the current uncertainty about these exposures' possible long-term health risks. This ethical framework can help clinicians and researchers consider and balance relevant concerns in deciding whether to inform offspring of HIV and related exposures.

Indexed as

DisclosureAnti-Retroviral AgentsConfidentialityFemaleHealth Insurance Portability and Accountability ActHIV InfectionsHumansInfectious Disease Transmission, VerticalMoralsPersonal AutonomyPregnancyPregnancy Complications, InfectiousPrenatal Exposure Delayed EffectsSocial JusticeSocial StigmaUnited StatesAnti-Retroviral Agents

Identifiers

PMID27310353
PMCPMC4940662
OpenAlexW2436483970

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.