Evidence map›Paper›PMID 27309628›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2016

Usefulness of direct fluorescent in buffy coat in the diagnosis of Candida sepsis in neonates.

M A Higareda-Almaraz, H Loza-Barajas, J G Maldonado-González, E Higareda-Almaraz, V Benítez-Godínez, E Murillo-Zamora

Erratum issuedAbstract readValidation Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

M A Higareda-AlmarazJefatura de Servicios de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Colima, Colima, México.
H Loza-BarajasDepartamento de Pediatría, Unidad Médica de Alta Especialidad, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
J G Maldonado-GonzálezDepartamento de Pediatría, Unidad Médica de Alta Especialidad, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.
E Higareda-AlmarazJefatura de Servicios de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Colima, Colima, México.
V Benítez-GodínezJefatura de Servicios de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Tepic, Nayarit, México.
E Murillo-ZamoraUnidad de Medicina Familiar No. 19, Instituto Mexicano del Seguro Social, Colima, Colima, México.
Mexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective of this study is to assess the clinical utility of direct fluorescent assay in buffy coat in the diagnosis of Candida sepsis (CS) in neonates. STUDY

designA cross-sectional study was conducted in a Neonatal Intensive Care Unit and 22 neonates with suspected CS were enrolled. Fungus isolation from blood cultures and direct fluorescent tests in buffy coat were performed and validity parameters were estimated.

resultsCandida was isolated in 13/22 (59%) blood cultures. The direct fluorescent test was positive in 12/13 and 1/9 cases with positive and negative blood culture as corresponding. Estimated sensitivity, specificity, positive predictive value, negative predictive value, positive likehood ratio and negative likehood ratio were 92%, 89%, 92%, 89%, 8.31 and 0.09, respectively.

conclusionThe direct fluorescent assay in buffy coat might be useful to support early and accurate diagnosis of CS in neonates.

Indexed as

Fluorescent Antibody Technique, DirectBlood Buffy CoatCandidaCandidemiaCross-Sectional StudiesEarly DiagnosisFemaleGestational AgeHumansInfantInfant, NewbornMaleMycological Typing TechniquesNeonatal SepsisPredictive Value of Tests

Identifiers

PMID27309628
OpenAlexW2421570906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.