Evidence map›Paper›PMID 27308736›Full record

ArticleAnnals of surgery2017

Impact of Volume Change Over Time on Trauma Mortality in the United States.

Joshua B Brown, Matthew R Rosengart, Jeremy M Kahn, Deepika Mohan, Brian S Zuckerbraun, Timothy R Billiar, Andrew B Peitzman, Derek C Angus, Jason L Sperry

Abstract read
In one paragraph

Article in Annals of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Are the life-saving interventions really life-saving?Trauma surgery & acute care open · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Process times of severely injured patients in the emergency room are associated with patient volume: a registry-based analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022
    Article
  10. Article
  11. Observational
  12. Observational
  13. Defining geographic emergency medical services coverage in trauma systems.The journal of trauma and acute care surgery · 2019
    Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joshua B Brown*Division of Trauma and General Surgery, Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA †Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA.
Matthew R Rosengart
Jeremy M Kahn
Deepika Mohan
Brian S Zuckerbraun
Timothy R Billiar
Andrew B Peitzman
Derek C Angus
Jason L Sperry

Funding

TRAINING IN TRAUMA AND SEPSIS RESEARCHT32GM008516 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TIMOTHY R BILLIAR · 1994 to 2026
$9.4M
NIGMS NIH HHS T32 GM008516
6 · The paper itself

Abstract

objectiveTo evaluate the association of trauma center volume change over time with mortality.

backgroundRegionalization of trauma systems assumes a volume-outcome relationship for severe injury. Whereas this has been shown for cross-sectional volume, it is unclear whether volume changes over time translate into predictable outcome changes.

methodsRetrospective cohort study of severely injured (injury severity score >15) patients from the National Trauma Databank 2000 to 2012. A center-level standardized mortality ratio (SMR) was constructed (ratio of observed to expected deaths). Expected mortality was obtained from multilevel logistic regression model, adjusting for demographics, mechanism, vital signs, and injury severity. Center-level percent volume change was assessed across early (2000-2006) and late (2007-2012) periods. Longitudinal panel modeling evaluated association between annual SMR change and volume change over preceding years.

resultsThere were 839,809 patients included from 287 centers. Each 1% increase in volume was associated with 73% increased odds of improving SMR over time [odds ratio (OR) 1.73; 95% confidence interval (CI) 1.03-2.91; P = 0.03]. Each 1% decrease in volume was associated with 2-fold increase in odds of worsening SMR over time (OR 2.14; 95% CI 1.07-4.26, P = 0.03). Significant improvement in the SMR emerged after 3 or more preceding years of increasing volume (SMR change -0.008; 95% CI -0.015, -0.002; P = 0.01). This benefit occurred only in centers that were level I or II verified.

conclusionsIncreasing volume was associated with improving outcomes, whereas decreasing volume was associated with worsening outcomes. High-level trauma center infrastructure seems to facilitate the volume-outcome relationship. The trauma center designation process should consider volume changes in the overall system.

Indexed as

AdultCross-Sectional StudiesFemaleHospital MortalityHumansInjury Severity ScoreMaleOutcome Assessment, Health CareRetrospective StudiesTrauma CentersUnited StatesWounds and Injuries

Identifiers

PMID27308736
PMCPMC12643027

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.