Evidence map›Paper›PMID 27308335›Full record

ReviewMolecular & cellular oncology

The Epithelial-to-Mesenchymal Transition (EMT), a Particular Case.

Joan Pau Cebrià-Costa, Alba Millanes-Romero, Antonio García de Herreros, Sandra Peiró

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular & cellular oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Joan Pau Cebrià-CostaPrograma de Recerca en Càncer; IMIM (Institut Hospital del Mar d'Investigacions Mèdiques) ; Barcelona, Spain.
Alba Millanes-RomeroInstitute for Research in Biomedicine (IRB Barcelona) ; Barcelona, Spain.
Antonio García de HerrerosPrograma de Recerca en Càncer; IMIM (Institut Hospital del Mar d'Investigacions Mèdiques); Barcelona, Spain; Departament de Ciències Experimentals i de la Salut; Universitat Pompeu Fabra; Barcelona, Spain.
Sandra PeiróPrograma de Recerca en Càncer; IMIM (Institut Hospital del Mar d'Investigacions Mèdiques) ; Barcelona, Spain.
Hospital del Mar Research Institute · ESInstitute for Research in Biomedicine · ESPompeu Fabra University · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Constitutive heterochromatin, an essential structure that has been conserved throughout evolution, is required to maintain genome stability. Although heterochromatin is enriched for repressive traits, it can be actively transcribed to generate thousands of noncoding RNAs that are required for correct chromatin assembly. Despite the importance of this structure, how and why heterochromatin transcription is regulated, and the proteins responsible for this regulation, remain poorly understood. Here, we summarize recent findings in heterochromatin transcription regulation during different cellular processes with a focus on the epithelial-mesenchymal transition (EMT), which elicits important changes in cell behavior, has a key role in early development, and is involved in cancer progression.

Indexed as

epithelial to mesenchymal transitionheterochromatinhistones

Identifiers

PMID27308335
PMCPMC4905179
OpenAlexW2011754010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.